Centaurin gamma 1 Antibody
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Catalog number
bs-5930R
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Price
Please ask
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Size
0.1ml
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Long name
Centaurin gamma 1 Primary Polyclonal Antibody
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Also known as
Centaurin gamma 1 PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
Centaurin gamma 1
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Specificity
This is a highly specific antibody against Centaurin gamma 1.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Centaurin gamma 1
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
Centaurin gamma 1; ANK repeat and PH domain-containing protein 2; AGAP-2; Agap2; Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; AGAP2_HUMAN; ANK repeat and PH domains 2; Arf GAP with GTP binding protein like; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; Arf GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2; Arf-GAP with GTPase; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; centaurin gamma1; Centaurin-gamma-1; Centg1; cnt g1; Cnt-g1; Cnt2; GGAP2; GTP binding and GTPase activating protein 2; GTP-binding and GTPase activating protein 2; GTP-binding and GTPase-activating protein 2; Nuclear GTPase PIKE; Phosphatidylinositol-3-kinase enhancer; Phosphoinositide 3 kinase enhancer; PI3K ENHANCER; PIKE.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
AGAP1, AGAP2, AGAP4
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Short name
Anti-Centaurin gamma 1
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
Centaurin gamma 1 Polyclonal Antibody
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Alternative technique
antibodies
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Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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