CENPB Antibody
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Catalog numberbs-6595R
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PricePlease ask
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Size0.1ml
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Long nameCENPB Primary Polyclonal Antibody
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Also known asCENPB PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenCENPB
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SpecificityThis is a highly specific antibody against CENPB.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationNucleus
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CENPB
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Gene ID number1059
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenThis gene product is a highly conserved protein associated with the centromere. It is a DNA-binding protein containing a helix loop helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17 bp sequence (CENPB box) in the centromeric satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere . (referenced from Entrez Gene)
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCENP B; CENP-B; centromere autoantigen B; Centromere protein B; Major centromere autoantigen B; CENPB_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCENPB
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Short nameAnti-CENPB
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameCENPB Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecentromere protein B
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Synonyms gene name
- centromere protein B (80kD)
- centromere protein B, 80kDa
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GenBank acession
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Locus
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Discovery year1988-05-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Helix-turn-helix CENPB type domain containing
- DNA transposon derived genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data