CDKN1A (Thr57) Antibody

  • Catalog number
    bs-5238R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    CDKN1A (Thr57) Primary Polyclonal Antibody
  • Also known as
    CDKN1A (Thr57) PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    CDKN1A Thr57
  • Specificity
    This is a highly specific antibody against CDKN1A Thr57. This phosphorylation site is homologous to Thr56 in Mouse.
  • Modification s
    Phosphorylation
  • Modification site s
    Thr57
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    30-70/164
  • Subcellular location
    Cytoplasm, Nucleus
  • Source
    KLH conjugated synthetic phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr57 [TE(p-T)PL]
  • Gene ID number
    1026
  • Swiss Prot
    P38936
  • Tested Applications
    IHC-P, IF(IHC-P)
  • Recommended dilutions
    IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; CDKN1A; MDA6; PIC1
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    CDKN1A   Thr57  
  • Gene symbol
    CDKN1A-AS1, CDKN1A
  • Short name
    Anti-CDKN1A Thr57
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    CDKN1A (Thr57) Polyclonal Antibody
  • Alternative technique
    antibodies
  • Alternative to gene target
    cyclin-dependent kinase inhibitor 1A (p21, Cip1), CAP20 and CDKN1 and CIP1 and MDA-6 and P21 and p21CIP1 and SDI1 and WAF1, CDKN1A and IDBG-85033 and ENSG00000124762 and 1026, metal ion binding, nuclei, Cdkn1a and IDBG-159848 and ENSMUSG00000023067 and 12575, CDKN1A and IDBG-630156 and ENSBTAG00000008353 and 513497
Gene info
  • Identity
  • Gene
  • Long gene name
    CDKN1A antisense RNA 1
  • Synonyms gene name
    • CDKN1A antisense RNA 1 (non-protein coding)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2011-07-11
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Antisense RNAs
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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