CDK4 Antibody ( DCS31)

• Catalog number
  MA1020
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  CDK4
• Clonality
  Monoclonal antibody
• Clone
  DCS-31
• Raised in
  mice
• Type of the antibody
  IgG2a monoclonal antibody
• Product form
  freeze-dried
• Reacts with species
  Human, mouse, rat
• Analyses
  WB,ICC
• Immunogen
  Recombinant human Cdk4 protein.
• Product configuration
  Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
• Purification
  Ascites
• Solubilization
  The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
• Storage condtions
  Keep the CDK4 Antibody ( DCS31)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The CDK4 Antibody ( DCS31) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Cyclin-dependent kinase-4(CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.
• Related articles
  1. Demetrick, D. J.; Zhang, H.; Beach, D. H. : Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes. Cytogenet. Cell Genet. 66: 72-74, 1994. 2. Modiano, J. F.; Mayor, J.; Ball, C.; Fuentes, M. K.; Linthicum, D. S. : CDK4 expression and activity are required for cytokine responsiveness in T cells. J. Immun. 165: 6693-6702, 2000.
• Gene Name
  CDK4
• Protein Name
  Cyclin-dependent kinase 4
• Gene Full Name
  cyclin-dependent kinase 4
• Synonyms
  PSK-J3|CELL DIVISION KINASE 4|Cell division protein kinase 4
• Uniprot ID
  Human(P11802), Mouse(P30285), Rat(P35462)
• Entrez GeneID
  Human(1019), Mouse(12567), Rat(94201)
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CDK4   DCS31  
• Gene symbol
  CDK4
• Short name
  CDK4 Antibody ( DCS31)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  cyclin-dependent kinase 4 (antibody to-) ( DCS31)
• Alternative technique
  antibodies
• Alternative to gene target
  cyclin-dependent kinase 4, CMM3 and PSK-J3, CDK4 and IDBG-43642 and ENSG00000135446 and 1019, transferase activity, nuclei, Cdk4 and IDBG-194056 and ENSMUSG00000006728 and 102641469,12567

Gene info

• Identity
  HGNC:1773
• Gene
  CDK4
• Long gene name
  cyclin dependent kinase 4
• Synonyms
  • PSK-J3
• GenBank acession
  • M14505
• Locus
  12q14.1
• Discovery year
  1993-07-28
• Entrez gene record
  1019
• Pubmed identfication
  • 8275715
• RefSeq identity
  • NM_000075
• Classification
  • Cyclin dependent kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000170382
• Locus Specific Databases
  • LRG_490

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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