CDH12 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-13715R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  CDH12 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-CDH12 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CDH12
• Specificity
  This is a highly specific antibody against CDH12.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDH12
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4). Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity (5,6). The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function (7). BR-cadherin (for brain-cadherin, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Br cadherin; BR-cadherin; Brain cadherin; CAD12_HUMAN; cadherin 12 N cadherin 2; Cadherin 12; Cadherin 12 precursor; Cadherin 12 type 2 N cadherin 2; Cadherin 12 type 2; Cadherin neural type 2; Cadherin-12; CDH12; CDHB; FLJ34857; N cadherin 2; N-cadherin 2; Neural type cadherin 2; Neuronal cadherin 2.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-CDH12 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  CDH12  
• Gene symbol
  CDH12
• Short name
  Anti-CDH12
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  CDH12 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  cadherin 12, type 2 (N-cadherin 2), CDHB, CDH12 and IDBG-13717 and ENSG00000154162 and 1010, calcium ion binding, Plasma membranes, Cdh12 and IDBG-130694 and ENSMUSG00000040452 and 215654, BT.41071 and IDBG-631013 and ENSBTAG00000025893 and 540672

Gene info

• Identity
  HGNC:1751
• Gene
  CDH12
• Long gene name
  cadherin 12
• Synonyms gene name
  • cadherin 12, type 2 (N-cadherin 2)
• Synonyms
  • Br-cadherin
  • CDHB
• GenBank acession
  • L33477
• Locus
  5p14.3
• Discovery year
  1995-07-14
• Entrez gene record
  1010
• Pubmed identfication
  • 7731968
• RefSeq identity
  • NM_004061
• Classification
  • Type II classical cadherins
• VEGA ID
  OTTHUMG00000090591

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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