CDC2 Antibody (CDK1)
-
Catalog numberF44350-0.08ML
-
PricePlease ask
-
Size0.08 ml
-
-
CategoryAntibody
-
ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
-
FormAntigen affinity purified
-
ConjugationUnconjugated
-
ClonePolyclonal antibody
-
Recognised antigenCDC2 (CDK1)
-
Host animalRabbit (Oryctolagus cuniculus)
-
ClonalityPolyclonal (rabbit origin)
-
Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
-
Tested applicationsWB, ELISA
-
Recommended dilutionsWestern blot: 1:1000
-
NotesTitration of the CDC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Intented useThis CDC2 antibodyis to be used only for research purposes and not for diagnostics..
-
UniprotP06493
-
PurityAntigen affinity
-
DescriptionCDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CDC2 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
-
ImmunogenA portion of amino acids 213-241 from the human protein was used as the immunogen for this CDC2 antibody.
-
StorageAliquot the CDC2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
-
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCDK1, POLD1
-
Short nameAnti-CDC2 (CDK1)
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeRabbit Ig
-
Alternative nameAntibodies to CDC2 (CDK1)
-
Alternative techniqueantibodies
-
Alternative to gene targetcyclin-dependent kinase 1, CDC2 and CDC28A and P34CDC2, CDK1 and IDBG-75344 and ENSG00000170312 and 983, transferase activity, nuclei, Cdk1 and IDBG-160472 and ENSMUSG00000019942 and 12534, CDK1 and IDBG-628960 and ENSBTAG00000010109 and 281061
-
Gene info
-
Identity
-
Gene
-
Long gene namecyclin dependent kinase 1
-
Synonyms gene
-
Synonyms gene name
- cell division cycle 2, G1 to S and G2 to M
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Cyclin dependent kinases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameDNA polymerase delta 1, catalytic subunit
-
Synonyms gene
-
Synonyms gene name
- polymerase (DNA directed), delta 1, catalytic subunit (125kD)
- polymerase (DNA) delta 1, catalytic subunit
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1992-02-06
-
Entrez gene record
-
Pubmed identfication
-
Classification
- DNA polymerases
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data