Cdc14A Antibody

• Catalog number
  bs-8614R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Cdc14A Primary Polyclonal Antibody
• Also known as
  Cdc14A PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Cdc14A
• Specificity
  This is a highly specific antibody against Cdc14A.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cdc14A
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  In budding yeast, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis. Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family. It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53. In addition, Cdc14a dephosphorylates hCdh1 and activates APCCdh1. Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, mitosis and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells. Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CDC 10; Cdc 14; Cdc 14A; Cdc 14A1; Cdc 14A2; CDC10; Cdc14; CDC14 cell division cycle 14 homolog A; CDC14 homolog A; Cdc14A1; Cdc14A2; Cell division cycle 14 homolog A; Dual specicity protein phosphatase CDC 14A; Dual specicity protein phosphatase CDC14A; hCDC14; CC14A_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cdc14A  
• Gene symbol
  CDC14A
• Short name
  Anti-Cdc14A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Cdc14A Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1718
• Gene
  CDC14A
• Long gene name
  cell division cycle 14A
• Synonyms gene
  • DFNB32
• Synonyms gene name
  • CDC10 (cell division cycle 10, S. cerevisiae, homolog)
  • CDC14 cell division cycle 14 homolog A (S. cerevisiae)
  • deafness, autosomal recessive 32
• Synonyms
  • Cdc14A1
  • Cdc14A2
  • cdc14
  • DFNB105
• GenBank acession
  • AF000367
• Locus
  1p21.2
• Discovery year
  1998-12-18
• Entrez gene record
  8556
• Pubmed identfication
  • 9367992
  • 10409437
  • 27259055
  • 29293958
• RefSeq identity
  • NM_033312
• Classification
  • CDC14 phosphatases
• VEGA ID
  OTTHUMG00000010987
• Locus Specific Databases
  • LRG_1418

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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