Transferrin receptor Antibody

  • Catalog number
    bs-0988R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    Transferrin receptor Primary Polyclonal Antibody
  • Also known as
    Transferrin receptor PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    Transferrin receptor
  • Specificity
    This is a highly specific antibody against Transferrin receptor.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    620-670/760
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Transferrin receptor
  • Gene ID number
    7037
  • Swiss Prot
    P02786
  • Tested Applications
    WB, FCM, IHC-P, IF(IHC-P), IF(ICC)
  • Recommended dilutions
    WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    T9; TR; TFR; p90; CD71; TFR1; TRFR; Transferrin receptor protein 1; TFRC
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    TFRC, TFR2
  • Short name
    Anti-Transferrin receptor
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    Transferrin receptor Polyclonal Antibody
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    transferrin receptor
  • Synonyms gene name
    • transferrin receptor (p90, CD71)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • Classification
    • M28 metallopeptidases
    • CD molecules
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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