CD16,32 (CD16, CD32, Fc-gamma RII, FcRII, Fcgr2, Fcgr2b, Fc-gamma RIII, FcRIII, Fcgr3, IgG Fc Receptor II beta, IgG Fc Receptor III, Low Affinity Immunoglobulin gamma Fc Region Receptor II, Low Affinity Immunoglobulin gamma Fc Region Receptor III)
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Catalog numberGEN649595
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PricePlease ask
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Size100ug
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Also known asCD16,32
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Other namesN/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesN/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2b,k
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Clone11K4
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Host organismMouse (Mus musculus)
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Source organismRat (Rattus norvegicus)
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Species reactivityRat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes rat FcR. Binds specifically to the Fc Receptor gamma III and II for all mouse strains tested. This antibody blocks Fc mediated binding of immunoglobulin to these molecules, and is useful as a means to block non specific binding in assays containing FcR expressing cell types.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein G affinity chromatography.
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Form AppearanceSupplied as a liquid in 50mM sodium phosphate pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 0.5mg/ml gentamicin sulfate.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsImmunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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TestA high affinity purification column was use to purify CD16 32 (CD16, CD32, Fc-gamma RII, FcRII, Fcgr2, Fcgr2b, Fc-gamma RIII, FcRIII, Fcgr3, IgG Fc Receptor II beta, IgG Fc Receptor III, Immunoglobulin gamma Fc Region Receptor II, Immunoglobulin gamma Fc Region Receptor III) by MBS Monoclonals by chromatographic size exclusion.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolCPLX3, MGAT3, MGST3, FCGR3A, FCGR3B, P4HA3, CASP5, THAP4, IGHVIII-82, MT-CSB3
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Short nameCD16 32 (CD16, CD32, Fc-gamma RII, FcRII, Fcgr2, Fcgr2b, Fc-gamma RIII, FcRIII, Fcgr3, IgG Fc Receptor II beta, IgG Fc Receptor III, Immunoglobulin gamma Fc Region Receptor II, Immunoglobulin gamma Fc Region Receptor III)
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Techniqueaffinity, IgG, FC, IgGs
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IsotypeIgG, IgG
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Alternative nameAnti-CD16,32 (CD16, CD32, Fc-gamma RII, FcRII, Fcgr2, Fcgr2b, Fc-gamma RIII, FcRIII, Fcgr3, IgG Fc Receptor II beta, IgG Fc Receptor III, Low Affinity Immunoglobulin gamma Fc Region Receptor II, Low Affinity Immunoglobulin gamma Fc Region Receptor III)
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Alternative techniqueimmunoglobulins
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Alternative to gene targetFc fragment of IgG, low affinity IIb, receptor (CD32), CD32 and CD32B and FCG2 and FCGR2 and IGFR2, FCGR2B and IDBG-104308 and ENSG00000072694 and 2213, IgG binding, Plasma membranes
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Tissueregion
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Gene info
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Identity
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Gene
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Long gene namecomplexin 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
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Synonyms gene name
- mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mannosyl-glycoprotein N-acetylglucosaminyltransferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicrosomal glutathione S-transferase 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-10-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Microsomal glutathione S-transferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFc gamma receptor IIIa
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Synonyms gene
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Synonyms gene name
- Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
- Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- Fc fragment of IgG receptor IIIa
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-11-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameFc gamma receptor IIIb
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Synonyms gene
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Synonyms gene name
- Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
- Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
- Fc fragment of IgG receptor IIIb
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-08-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameprolyl 4-hydroxylase subunit alpha 3
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Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
- prolyl 4-hydroxylase, alpha polypeptide III
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-05-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 5
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Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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Locus
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Discovery year1996-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTHAP domain containing 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-10-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- THAP domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (III)-82 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (III)-82
- immunoglobulin heavy variable (III)-82 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemitochondrially encoded conserved sequence block III
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Synonyms gene
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Synonyms gene name
- conserved sequence block III
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Synonyms
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Locus
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Discovery year1989-10-11
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Pubmed identfication
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Classification
- Mitochondrially encoded regions