CD3 Antibody ( CA3)

• Catalog number
  MA1015
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  CD3
• Clonality
  Monoclonal antibody
• Clone
  CA-3
• Raised in
  mice
• Type of the antibody
  IgG1 monoclonal antibody
• Product form
  freeze-dried
• Reacts with species
  Human
• Analyses
  IHC-F
• Immunogen
  Human thymocytes followed by Sezary T cells.
• Product configuration
  Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
• Purification
  Ascites
• Solubilization
  The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
• Storage condtions
  Keep the CD3 Antibody ( CA3)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The CD3 Antibody ( CA3) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3(formerly T3). Human CD3 consists of at least 4 proteins: gamma, delta, epsilon, and zeta. The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development.
• Related articles
  1. Krissansen, G. W.; Owen, M. J.; Verbi, W.; Crumpton, M. J. : Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits. EMBO J. 5: 1799-1808, 1986. 2. Tunnacliffe, A.; Buluwela, L.; Rabbitts, T. H. : Physical linkage of three CD3 genes on human chromosome 11. EMBO J. 6: 2953-2957, 1987.
• Gene Name
  CD3E
• Protein Name
  T-cell surface glycoprotein CD3 epsilon chain
• Gene Full Name
  CD3e molecule, epsilon(CD3-TCR complex)
• Synonyms
  T3E|T-cell surface antigen T3/Leu-4 epsilon chain
• Uniprot ID
  Human(P07766), Mouse(P22646), Rat(D4A5M2)
• Entrez GeneID
  Human(916), Mouse(12501), Rat(315609)
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD3   CA3  
• Gene symbol
  CA3-AS1, CA3
• Short name
  CD3 Antibody ( CA3)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  CD3 (antibody to-) ( CA3)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:51657
• Gene
  CA3-AS1
• Long gene name
  CA3 antisense RNA 1
• Locus
  8q21.2
• Discovery year
  2015-04-24
• Entrez gene record
  100996348
• RefSeq identity
  • NR_121630
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000164943

Gene info

• Identity
  HGNC:1374
• Gene
  CA3
• Long gene name
  carbonic anhydrase 3
• Synonyms gene name
  • carbonic anhydrase III, muscle specific
  • carbonic anhydrase III
• Synonyms
  • Car3
  • CAIII
• GenBank acession
  • AJ006473
• Locus
  8q21.2
• Discovery year
  2001-06-22
• Entrez gene record
  761
• Pubmed identfication
  • 6221502
• RefSeq identity
  • NM_005181
• Classification
  • Carbonic anhydrases
• VEGA ID
  OTTHUMG00000164942

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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