CD278(ICOS)-muIg-Biotin

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Properties

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated

Gene target

CD278 ICOS muIg
Gene symbol

ICOS, ICOSLG
Short name

CD278(ICOS)-muIg-
Label

Biotin
Alternative name

CD278(inducible T-cell co-stimulator)-muIg-biotinilated
Alternative to gene target

inducible T-cell co-stimulator, ICOS and IDBG-79246 and ENSG00000163600 and 29851, protein binding, Extracellular, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026

Identity

HGNC:5351
Gene

ICOS
Long gene name

inducible T cell costimulator
Synonyms gene name
- inducible T-cell costimulator
Synonyms
- AILIM
- CD278
Synonyms name
- activation-inducible lymphocyte immunomediatory molecule
GenBank acession
- AB023135
Locus

2q33.2
Discovery year

2000-02-29
Entrez gene record

29851
Pubmed identfication
- 9930702
- 10617205
RefSeq identity
- NM_012092
Classification
- CD molecules
VEGA ID

OTTHUMG00000132880
Locus Specific Databases
- ICOSbase: Mutation registry for ICOS deficiency
- LRG_65