CD160 Polyclonal Antibody
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Catalog number
A1072-100
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Price
Please ask
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Size
100 µl
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Antibody Target
CD160
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Target Alternative Name
CD160 antigen, Natural killer cell receptor BY55, CD160, CD160, BY55
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Antibody Type
Polyclonal
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Species Reactivities
Human
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Immunogen Sequence
KLH conjugated synthetic peptide between 56-82 amino acids from the Central region of human CD160.
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Accession
O95971
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Gene Id
11126
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
PBS with 0.09% (W/V) sodium azide.
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Purification
Protein A column, followed by peptide affinity purification.
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Application
WB
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Positive Control
WB
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Application And Usages
WB: 1:1001
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Description
CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+ CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans
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Handling
The antibody solution should be gently mixed before use
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translation
anticorps
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Gene target
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Gene symbol
CD160
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Short name
CD160 Polyclonal Antibody
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Technique
Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Isotype
Rabbit IgG
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Alternative name
CD160 molecule polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies
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Alternative to gene target
CD160 molecule, BY55 and NK1 and NK28, CD160 and IDBG-101772 and ENSG00000117281 and 11126, MHC class I receptor activity, Plasma membranes, Cd160 and IDBG-176450 and ENSMUSG00000038304 and 54215
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Gene info
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Identity
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Gene
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Long gene name
CD160 molecule
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-10-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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