Integrin alpha 1 Antibody
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Catalog number
R30223
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Price
Please ask
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Size
0.1mg
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Category
Antibody
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Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
Integrin alpha 1
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB, IHC-P
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Recommended dilutions
Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
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Notes
The stated application concentrations are suggested starting amounts. Titration of the Integrin alpha 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented use
This Integrin alpha 1 antibodyis to be used only for research purposes and not for diagnostics..
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Uniprot
P56199
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Purity
Antigen affinity
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Description
Integrin alpha 1(ITGA1) chain associates with the beta 1(ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
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Immunogen
An amino acid sequence from the C-terminus of human Integrin alpha 1 (SNQKRELAIQISKD) was used as the immunogen for this Integrin alpha 1 antibody.
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Storage
After reconstitution, the Integrin alpha 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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Additional description
The Anti-Integrin alpha 1 is a α- or alpha protein sometimes glycoprotein present in blood.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ITGA1, ITGAM, ITGAE
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Short name
Anti-Integrin alpha 1
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
Antibodies to Integrin alpha 1
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
integrin subunit alpha 1
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Synonyms gene name
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1992-02-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Integrin alpha subunits
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
integrin subunit alpha M
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Synonyms gene
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Synonyms gene name
- integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)
- integrin, alpha M (complement component 3 receptor 3 subunit)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1988-08-05
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Entrez gene record
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RefSeq identity
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Classification
- Integrin alpha subunits
- Complement system regulators and receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
integrin subunit alpha E
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Synonyms gene name
- integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Integrin alpha subunits
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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