CCL4/MIP1 beta Antibody
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Catalog numberPB9064
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PricePlease ask
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Size0,1 mg
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Target antigenCCL4/MIP1 beta
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with speciesHuman, Mouse, Rat. No cross reactivity with other proteins.
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AnalysesWB
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ImmunogenE.coli-derived rat CCL4 recombinant protein (Position: A24-N92). Rat CCL4 shares 80% and 86% amino acid (aa) sequences identity with human and mouse CCL4, respectively.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the CCL4/MIP1 beta Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe CCL4/MIP1 beta Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundChemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).
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Related articles1. Irving SG, Zipfel PF, Balke J, McBride OW, Morton CC, Burd PR, Siebenlist U, Kelly K (June 1990). Nucleic Acids Res. 18 (11): 3261–70. 2. Bystry RS, Aluvihare V, Welch KA, Kallikourdis M, Betz AG (December 2001). "B cells and professional APCs recruit regulatory T cells via CCL4". Nat. Immunol. 2 (12): 1126–32. 3. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P (December 1995). Science (journal) 270 (5243): 1811–5. 4. Kamin-Lewis R, Abdelwahab SF, Trang C, Baker A, DeVico AL, Gallo RC, Lewis GK (July 2001).
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Gene NameCCL4
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Protein NameC-C motif chemokine 4
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Gene Full Namechemokine (C-C motif) ligand 4
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SynonymsMIP 1 beta antibody|Secreted protein G 26 antibody|ACT 2 antibody|ACT-2 antibody|ACT2 antibody|AT744.1 antibody|AT744.2 antibody|C C motif chemokine 4 antibody|C C motif chemokine 4 like antibody|CC chemokine ligand 4 antibody|CC chemokine ligand 4L1d2 antibody|CC chemokine ligand 4L2 antibody|CCL4 antibody|CCL4_HUMAN antibody|ccl4l 1 antibody|CCL4L antibody|CCL4L1 antibody|Chemokine (C C motif) ligand 4 antibody|Chemokine (C C motif) ligand 4 like 1 antibody|Chemokine (C C motif) ligand 4 like 1, telomeric antibody|Chemokine (C C motif) ligand 4 like 2 antibody|Chemokine CC Motif Ligand 4 antibody|G 26 antibody|G 26 T lymphocyte secreted protein antibody|G-26 T-lymphocyte-secreted protein antibody|HC21 antibody|LAG 1 antibody|LAG-1 antibody|LAG1 antibody|Lymphocyte activation gene 1 antibody|Lymphocyte activation gene 1 protein antibody|Macrophage inflammatory protein 1 beta antibody|Macrophage inflammatory protein 1-beta antibody|Macrophage inflammatory protein 1b2 antibody|MGC104418 antibody|MGC126025 antibody|MGC126026 antibody|MIP 1 beta antibody|MIP-1-beta antibody|MIP-1-beta(1-69) antibody|MIP-1-beta(3-69) antibody|MIP1 beta antibody|MIP1B antibody|MIP1B1 antibody|Monocyte adherence induced protein 5 alpha antibody|PAT 744 antibody|Protein H400 antibody|SCYA2 antibody|SCYA4 antibody|SCYA4L antibody|Secreted protein G 26 antibody|Secreted protein G26 antibody|SIS gamma antibody|SIS-gamma antibody|Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody|Small inducible cytokine A4 antibody|Small-inducible cytokine A4 antibody|T cell activation protein 2 antibody|T-cell activation protein 2 antibody
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Uniprot IDP50230
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Entrez GeneID116637
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMAPKAP1, RPTOR, TNPO1, CCL4
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Short nameCCL4/MIP1 beta Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameCCL4/MIP1 b (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameMAPK associated protein 1
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Synonyms gene name
- mitogen-activated protein kinase associated protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-07-19
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Entrez gene record
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Pubmed identfication
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Classification
- MTOR complex 2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameregulatory associated protein of MTOR complex 1
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Synonyms gene name
- regulatory associated protein of MTOR, complex 1
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Synonyms
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Synonyms name
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Locus
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Discovery year2009-05-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- MTOR complex 1
- Armadillo like helical domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametransportin 1
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Synonyms gene
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Synonyms gene name
- karyopherin (importin) beta 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Importins
- Armadillo like helical domain containing
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 4
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Synonyms gene
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Synonyms gene name
- small inducible cytokine A4 (homologous to mouse Mip-1b)
- chemokine (C-C motif) ligand 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-07-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data