CCL4/MIP1 beta Antibody

  • Catalog number
    PB9064
  • Price
    Please ask
  • Size
    0,1 mg
  • Target antigen
    CCL4/MIP1 beta
  • Clonality
    Polyclonal antibody
  • Clone
    Polyclonal antibody
  • Raised in
    rabbit
  • Type of the antibody
    IgG polyclonal antibody
  • Product form
    freeze-dried
  • Reacts with species
    Human, Mouse, Rat. No cross reactivity with other proteins.
  • Analyses
    WB
  • Immunogen
    E.coli-derived rat CCL4 recombinant protein (Position: A24-N92). Rat CCL4 shares 80% and 86% amino acid (aa) sequences identity with human and mouse CCL4, respectively.
  • Product configuration
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
  • Purification
    Immunogen affinity purified.
  • Solubilization
    The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
  • Storage condtions
    Keep the CCL4/MIP1 beta Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The CCL4/MIP1 beta Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).
  • Related articles
    1. Irving SG, Zipfel PF, Balke J, McBride OW, Morton CC, Burd PR, Siebenlist U, Kelly K (June 1990). Nucleic Acids Res. 18 (11): 3261–70. 2. Bystry RS, Aluvihare V, Welch KA, Kallikourdis M, Betz AG (December 2001). "B cells and professional APCs recruit regulatory T cells via CCL4". Nat. Immunol. 2 (12): 1126–32. 3. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P (December 1995). Science (journal) 270 (5243): 1811–5. 4. Kamin-Lewis R, Abdelwahab SF, Trang C, Baker A, DeVico AL, Gallo RC, Lewis GK (July 2001).
  • Gene Name
    CCL4
  • Protein Name
    C-C motif chemokine 4
  • Gene Full Name
    chemokine (C-C motif) ligand 4
  • Synonyms
    MIP 1 beta antibody|Secreted protein G 26 antibody|ACT 2 antibody|ACT-2 antibody|ACT2 antibody|AT744.1 antibody|AT744.2 antibody|C C motif chemokine 4 antibody|C C motif chemokine 4 like antibody|CC chemokine ligand 4 antibody|CC chemokine ligand 4L1d2 antibody|CC chemokine ligand 4L2 antibody|CCL4 antibody|CCL4_HUMAN antibody|ccl4l 1 antibody|CCL4L antibody|CCL4L1 antibody|Chemokine (C C motif) ligand 4 antibody|Chemokine (C C motif) ligand 4 like 1 antibody|Chemokine (C C motif) ligand 4 like 1, telomeric antibody|Chemokine (C C motif) ligand 4 like 2 antibody|Chemokine CC Motif Ligand 4 antibody|G 26 antibody|G 26 T lymphocyte secreted protein antibody|G-26 T-lymphocyte-secreted protein antibody|HC21 antibody|LAG 1 antibody|LAG-1 antibody|LAG1 antibody|Lymphocyte activation gene 1 antibody|Lymphocyte activation gene 1 protein antibody|Macrophage inflammatory protein 1 beta antibody|Macrophage inflammatory protein 1-beta antibody|Macrophage inflammatory protein 1b2 antibody|MGC104418 antibody|MGC126025 antibody|MGC126026 antibody|MIP 1 beta antibody|MIP-1-beta antibody|MIP-1-beta(1-69) antibody|MIP-1-beta(3-69) antibody|MIP1 beta antibody|MIP1B antibody|MIP1B1 antibody|Monocyte adherence induced protein 5 alpha antibody|PAT 744 antibody|Protein H400 antibody|SCYA2 antibody|SCYA4 antibody|SCYA4L antibody|Secreted protein G 26 antibody|Secreted protein G26 antibody|SIS gamma antibody|SIS-gamma antibody|Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody|Small inducible cytokine A4 antibody|Small-inducible cytokine A4 antibody|T cell activation protein 2 antibody|T-cell activation protein 2 antibody
  • Uniprot ID
    P50230
  • Entrez GeneID
    116637
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    CCL4/MIP1   beta  
  • Gene symbol
    MAPKAP1, RPTOR, TNPO1, CCL4
  • Short name
    CCL4/MIP1 beta Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    CCL4/MIP1 b (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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