CBP, CREB-binding protein homolog

Available ordering format

Lyophilized in PBS pH 7.4
Immunogen

Recombinant CBP part, fused to GST, derived from O01368
Raised in

Rabbit
Clonality

Polyclonal
Clone

Polyclonal
Purification

Affinity purified serum
How to reconstitute

For reconstitution add 50 µl of sterile water.
Storage condition

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Verified applications

western blot (WB)
Connected products

Secondary antibodies
Recommended dilutions for use

1 : 500 with standard ECL (WB), 3 µg (ChIP)
Molecular weight expected аpparent

331 kDa
Verified reactivity

Drosophila melanogaster
Possible reactivity

Drosophila melanogaster
No reactivity

no confirmed exceptions from predicted reactivity are currently known
Supplementary information

to be added when available
References

to be added when available, antibody released in March 2014.
Scientific context

CBP (CREB-binding protein homolog) is a transcriptional coactivator in multiple signal transduction pathways. It might play a role in variety of cellular processes, including differentiation, cellular proliferation, immune response, homeostasis, tumorigenesis, and erganogenesis.
Notes

None
Protein number

Refer to NCBI
TAIR number

Refer to NCBI
Hyperlink

Identity

HGNC:786
Gene

ATF4
Long gene name

activating transcription factor 4
Synonyms gene
- TXREB
Synonyms gene name
- activating transcription factor 4 (tax-responsive enhancer element B67)
Synonyms
- TAXREB67
- CREB-2
Synonyms name
- tax-responsive enhancer element B67
GenBank acession
- D90209
Locus

22q13.1
Discovery year

1992-06-09
Entrez gene record

468
Pubmed identfication
- 1847461
- 1534408
RefSeq identity
- NM_001675
Classification
- Basic leucine zipper proteins
VEGA ID

OTTHUMG00000151099

Identity

HGNC:30043
Gene

PAG1
Long gene name

phosphoprotein membrane anchor with glycosphingolipid microdomains 1
Synonyms gene name
- phosphoprotein associated with glycosphingolipid microdomains 1
Synonyms
- PAG
- CBP
Synonyms name
- Csk-binding protein
- transmembrane adaptor protein PAG
GenBank acession
- AF240634
Locus

8q21.13
Discovery year

2005-04-25
Entrez gene record

55824
Pubmed identfication
- 10790433
RefSeq identity
- NM_018440
VEGA ID

OTTHUMG00000164592

Identity

HGNC:9936
Gene

OPN1LW
Long gene name

opsin 1, long wave sensitive
Synonyms gene
- CBBM
- RCP
- CBP
Synonyms gene name
- color blindness, protan
- red cone photoreceptor pigment
- opsin 1 (cone pigments), long-wave-sensitive
Synonyms
- COD5
Synonyms name
- cone dystrophy 5 (X-linked)
GenBank acession
- Z68193
Locus

Xq28
Discovery year

2001-06-22
Entrez gene record

5956
RefSeq identity
- NM_020061
Classification
- Opsin receptors
VEGA ID

OTTHUMG00000034295
Locus Specific Databases
- Mutations of the Photopigments - Red (RCP), Green (GCP), and Blue Cone Pigment (BCP)

Identity

HGNC:2348
Gene

CREBBP
Long gene name

CREB binding protein
Synonyms gene
- RSTS
Synonyms gene name
- Rubinstein-Taybi syndrome
Synonyms
- RTS
- CBP
- KAT3A
GenBank acession
- U85962
Locus

16p13.3
Discovery year

1995-01-10
Entrez gene record

1387
Pubmed identfication
- 8413673
RefSeq identity
- NM_004380
Classification
- Bromodomain containing
- Zinc fingers ZZ-type
- Lysine acetyltransferases
VEGA ID

OTTHUMG00000129431
Locus Specific Databases
- Global Variome shared LOVD
- LRG_1426