Cathepsin B&L Inhibitor Z-Phe-Phe-FMK
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Catalog number
1126-20C
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Price
Please ask
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Size
20 ul (10 mM)
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Alternative_name
Z-FF-FMK, Cathepsin B&L Inhibitor(fluoromethylketone)
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Description
A potent, cell-permeable, and irreversible inhibitor of Cathepsin B and L.
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Structure Available
No
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Peptide sequence
Z-Phe-Phe-FMK
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Salt Form
No
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Molecular Formula
C₂₇H₂₇FN₂O₄
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Molecular Weight
462.5
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Cell Permeable
Yes
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Purity
>95% by HPLC
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Handling
Protect from light and moisture
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Tag Line
A Cathepsin B & L inhibitor
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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MDL Number
MFCD03453604
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PubChem CID
16760359
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SMILES
C1=CC=C(C=C1)CC(C(=O)CF)NC(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3
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InChi
InChI=1S/C27H27FN2O4/c28-18-25(31)23(16-20-10-4-1-5-11-20)29-26(32)24 (17-21-12-6-2-7-13-21)30-27(33)34-19-22-14-8-3-9-15-22/h1-15,23-24H, 16-19H2,(H,29,32)(H,30,33)
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InChi Key
CAILNONEKASNSH-UHFFFAOYSA-N
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MSDS Available
Yes
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Gene
CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
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Additional description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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