Caspase-2 Substrate VDVAD-pNA

• Catalog number
  1072-1000
• Price
  Please ask
• Size
  1000 assays

• Alternative_name
  Ac-VDVAD-pNA, Caspase-2 Substrate, Colorimetric, VDVAD-pNA
• Description
  Ready-to-use colorimetric substrate for caspase-2/Ich-1 and related caspases that recognize the amino acid sequence VDVAD. Caspase-2 and related caspase activity can be quantified by detection of free pNA after cleavage from the peptide substrate VDVAD-pNA at OD405 nm using a spectrophotometer or plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large amount of caspase assays.
• Structure Available
  No
• Peptide sequence
  Ac-Val-Asp-Val-Ala-Asp-pNA
• Salt Form
  No
• Molecular Formula
  C₂₉H₄₁N₇O₁₂
• Molecular Weight
  679.7
• Cell Permeable
  No
• Purity
  >98% by HPLC
• Handling
  Protect from light and moisture
• Tag Line
  A caspase-2 substrate
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• PubChem CID
  44135308
• PubChem CID Link
• SMILES
  CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C
• InChi
  InChI=1S/C29H41N7O12/c1-13(2)23(31-16(6)37)29(46)34-20(12-22(40)41)27(44)35-24(14(3)4)28(45)30-15(5)25(42)33-19(11-21(38)39)26(43)32-17-7-9-18(10-8-17)36(47)48/h7-10,13-15,19-20,23-24H,11-12H2,1-6H3,(H,30,45)(H,31,37)(H,32,43)(H,33,42)(H,34,46)(H,35,44)(H,38,39)(H,40,41)
• InChi Key
  SIOKOOKURWWOID-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes
• Additional description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

• Gene target
  Caspase-2   Substrate   VDVAD-pNA  
• Short name
  Caspase-2 Substrate VDVAD-pNA
• Alternative name
  caspase-2 Substrate VDVAD-pNA

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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