CARD4 Antibody
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Catalog numberbs-7085R
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PricePlease ask
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Size0.1ml
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Long nameCARD4 Primary Polyclonal Antibody
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Also known asCARD4 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenCARD4
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SpecificityThis is a highly specific antibody against CARD4.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range64-105/953
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Subcellular locationHelical
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD4
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Gene ID number10392
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Swiss ProtQ9Y239
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenEnhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following bacterial infection.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCARD4; NLRC1; CLR7.1; Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4; NOD1
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNOD1
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Short nameAnti-CARD4
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameCARD4 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namenucleotide binding oligomerization domain containing 1
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Synonyms gene
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Synonyms gene name
- caspase recruitment domain family, member 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-12-11
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Entrez gene record
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Pubmed identfication
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Classification
- NLR family
- Caspase recruitment domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data