Carcinoembryonic Antigen (CEA) Mouse Monoclonal Antibody (C234)

• Catalog number
  MBS588366
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Carcinoembryonic Antigen (CEA)]
• Other_names
  [carcinoembryonic antigen, partial; Carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD_antigen: CD66e]
• Products_gene_name
  [CEA]
• Other_gene_names
  [CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA]
• Clonality
  Monoclonal
• Clone
  [C234]
• Reactivity
  Human
• Specificity
  This antibody is CEA specific. It does not recognize NCA, neither in enzyme linked immunosorbent assay (ELISA) not on Western blots of crude tissue extracts. This antibody binds to CEA producing human adenocarcinoma cells (e.g. LS174T,WiDr) but does not bind to CEA non-secreting human adenocarcinoma cells (Colo 320DM). It does not immunostain cryocuts of any normal human tissues tested (artery, heart muscle, kidney, large bowel, liver, lung, skeletal muscle, skin, small gut, spleen, testes or vein) neither does it react with any antigens on human blood cells when separated by fluoresceine actuated cell sorter (FACS). Immunohistochemical analysis of cancerous tissues revealed that the antibody bound selectively adenocarcinoma and not carcinoid tumor of the colon, as well as tumor-associated CEA in breast, gastric and lung neoplasms, while there was no immunohistochemical evidence of cross-reactivity with NCA. A remarkable feature of this antibody is its ability to distinguish immunohistochemically between cancer and residual normal tissue within the same organ.
• Form
  Lyophilized Protein A purified in PBS pH7.4 (Full IgG)
• Storage_stability
  Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C). For maximum recovery of product centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EIA), Immunohistochemistry (IHC)
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Antigens are peptides or recombinant or native dependent on the production method.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Carcinoembryonic   CEA   Monoclonal   C234  
• Gene symbol
  CEACAM7, CEACAM5, PSG2
• Short name
  Carcinoembryonic Antigen (CEA) Mouse Monoclonal Antibody (C234)
• Technique
  Mouse monoclonal, Antibody, antigen, Mouse, antibodies against human proteins, antibodies for, antigenes, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG kappa
• Species
  Mouse, Mouses
• Alternative name
  Carcinoembryonic protein (CEA) Mouse monoclonal (antibody to-) (C234)
• Alternative technique
  antibodies, antigenes, murine

Gene info

• Identity
  HGNC:1819
• Gene
  CEACAM7
• Long gene name
  CEA cell adhesion molecule 7
• Synonyms gene
  • CGM2
• Synonyms gene name
  • carcinoembryonic antigen-related cell adhesion molecule 7
  • carcinoembryonic antigen related cell adhesion molecule 7
• Synonyms
  • CEA
• Synonyms name
  • carcinoembryonic antigen gene family member 2
• GenBank acession
  • X98311
• Locus
  19q13.2
• Discovery year
  1991-09-12
• Entrez gene record
  1087
• Pubmed identfication
  • 7806520
  • 9135022
• RefSeq identity
  • NM_006890
• Classification
  • V-set domain containing
  • CEA cell adhesion molecule family
• VEGA ID
  OTTHUMG00000151063

Gene info

• Identity
  HGNC:1817
• Gene
  CEACAM5
• Long gene name
  CEA cell adhesion molecule 5
• Synonyms gene
  • CEA
• Synonyms gene name
  • carcinoembryonic antigen-related cell adhesion molecule 5
  • carcinoembryonic antigen related cell adhesion molecule 5
• Synonyms
  • CD66e
• GenBank acession
  • M17303
• Locus
  19q13.2
• Discovery year
  1986-01-01
• Entrez gene record
  1048
• RefSeq identity
  • NM_004363
• Classification
  • I-set domain containing
  • V-set domain containing
  • CEA cell adhesion molecule family
  • CD molecules
• VEGA ID
  OTTHUMG00000151061

Gene info

• Identity
  HGNC:9519
• Gene
  PSG2
• Long gene name
  pregnancy specific beta-1-glycoprotein 2
• Synonyms gene
  • PSBG2
• Synonyms
  • PSGGB
  • PSG1
  • CEA
• Synonyms name
  • pregnancy-specific beta-1 glycoprotein
  • pregnancy-specific beta-1-glycoprotein 7
  • carcinoembryonic antigen SG8
• Locus
  19q13.31
• Discovery year
  1991-06-06
• Entrez gene record
  5670
• Pubmed identfication
  • 2377620
• RefSeq identity
  • NM_031246
• Classification
  • Pregnancy specific glycoproteins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000151547

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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