Canertinib (CI-1033), kinase Inhibitor of Her2/Erb2/EGFR (mol wt 485; >98%)

• Catalog number
  SM-101070-10
• Price
  Please ask
• Size
  10 mg

• Stock availability
  Available
• Category
  Custom Service
• Antibody type
  N/A
• Antibody host
  N/A
• Antibody conjugate
  N/A
• Technical datasheet
  Contact Gentaur to request the datasheet or ask our specialists for more information.
• Notes
  The Canertinib (CI-1033), kinase Inhibitor of Her2/Erb2/EGFR (mol wt 485; >98%) is manufactured for Research Use Only or for diagnostics purposes.
• Other related products
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Canertinib   CI-1033   kinase   Inhibitor   Her2/Erb2/EGFR   mol   485   >98  
• Gene symbol
  EGFR-AS1, EGILA, EGFR, NDUFV3, NDUFA5, NDUFV2, NDUFA10, NDUFS1, NDUFS6, NDUFS2
• Short name
  Canertinib (CI-1033), kinase Inhibitor of Her2/Erb2/EGFR (mol wt 485; >98%)
• Species
  N/A
• Alternative name
  Canertinib (CI-1033), phosphorylation catalyst suppressor on Her2/Erb2/epidermal growth factor receptor (mol wt 485; >98%)
• Alternative to gene target
  epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217

Gene info

• Identity
  HGNC:40207
• Gene
  EGFR-AS1
• Long gene name
  EGFR antisense RNA 1
• Locus
  7p11.2
• Discovery year
  2012-11-06
• Entrez gene record
  100507500
• Pubmed identfication
  • 26271667
  • 28920960
• RefSeq identity
  • NR_047551
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156126

Gene info

• Identity
  HGNC:54482
• Gene
  EGILA
• Long gene name
  EGFR interacting lncRNA
• Synonyms
  • Lnc-EGFR
• Locus
  14q11.2
• Discovery year
  2019-09-27
• Pubmed identfication
  • 28541302
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:3236
• Gene
  EGFR
• Long gene name
  epidermal growth factor receptor
• Synonyms gene
  • ERBB
• Synonyms gene name
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
• Synonyms
  • ERBB1
  • ERRP
• Synonyms name
  • erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian)
  • erb-b2 receptor tyrosine kinase 1
• Locus
  7p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  1956
• Pubmed identfication
  • 1505215
• RefSeq identity
  • NM_005228
• Classification
  • Erb-b2 receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000023661
• Locus Specific Databases
  • LRG_304

Gene info

• Identity
  HGNC:7719
• Gene
  NDUFV3
• Long gene name
  NADH:ubiquinone oxidoreductase subunit V3
• Synonyms gene name
  • NADH dehydrogenase (ubiquinone) flavoprotein 3 (10kD)
  • NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
• Synonyms
  • CI-10k
• Synonyms name
  • complex I 10kDa subunit
• Locus
  21q22.3
• Discovery year
  1994-09-07
• Entrez gene record
  4731
• Pubmed identfication
  • 9344673
• Classification
  • NADH:ubiquinone oxidoreductase supernumerary subunits
• VEGA ID
  OTTHUMG00000086823

Gene info

• Identity
  HGNC:7688
• Gene
  NDUFA5
• Long gene name
  NADH:ubiquinone oxidoreductase subunit A5
• Synonyms gene name
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13)
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
• Synonyms
  • B13
  • NUFM
  • CI-13KD-B
  • UQOR13
  • CI-13kB
• Synonyms name
  • complex I 13kDa subunit B
  • ubiquinone reductase
  • type I dehydrogenase
  • NADH-ubiquinone oxidoreductase 13 kDa-B subunit
• Locus
  7q31.32
• Discovery year
  1996-08-30
• Entrez gene record
  4698
• Pubmed identfication
  • 9763677
  • 9021153
• RefSeq identity
  • NM_005000
• Classification
  • NADH:ubiquinone oxidoreductase supernumerary subunits
• VEGA ID
  OTTHUMG00000157348

Gene info

• Identity
  HGNC:7717
• Gene
  NDUFV2
• Long gene name
  NADH:ubiquinone oxidoreductase core subunit V2
• Synonyms gene name
  • NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
• Synonyms
  • CI-24k
• Synonyms name
  • complex I 24kDa subunit
  • NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
• GenBank acession
  • X84421
• Locus
  18p11.22
• Discovery year
  1994-09-07
• Entrez gene record
  4729
• Pubmed identfication
  • 9763677
  • 7607668
• RefSeq identity
  • NM_021074
• Classification
  • NADH:ubiquinone oxidoreductase core subunits
• VEGA ID
  OTTHUMG00000131593

Gene info

• Identity
  HGNC:7684
• Gene
  NDUFA10
• Long gene name
  NADH:ubiquinone oxidoreductase subunit A10
• Synonyms gene name
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD)
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
• Synonyms
  • CI-42k
• Synonyms name
  • complex I 42kDa subunit
• GenBank acession
  • AF087661
• Locus
  2q37.3
• Discovery year
  1997-12-17
• Entrez gene record
  4705
• Pubmed identfication
  • 9878551
• RefSeq identity
  • NM_004544
• Classification
  • NADH:ubiquinone oxidoreductase supernumerary subunits
• VEGA ID
  OTTHUMG00000133350

Gene info

• Identity
  HGNC:7707
• Gene
  NDUFS1
• Long gene name
  NADH:ubiquinone oxidoreductase core subunit S1
• Synonyms gene name
  • NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD) (NADH-coenzyme Q reductase)
  • NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
• Synonyms
  • CI-75k
• Synonyms name
  • complex I 75kDa subunit
  • NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
• Locus
  2q33.3
• Discovery year
  1992-04-03
• Entrez gene record
  4719
• Pubmed identfication
  • 1935949
• RefSeq identity
  • NM_005006
• Classification
  • NADH:ubiquinone oxidoreductase core subunits
• VEGA ID
  OTTHUMG00000132892

Gene info

• Identity
  HGNC:7713
• Gene
  NDUFS6
• Long gene name
  NADH:ubiquinone oxidoreductase subunit S6
• Synonyms gene name
  • NADH dehydrogenase (ubiquinone) Fe-S protein 6 (13kD) (NADH-coenzyme Q reductase)
  • NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
• Synonyms
  • CI-13kA
• Synonyms name
  • complex I 13kDa subunit A
  • NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
• GenBank acession
  • BC038664
• Locus
  5p15.33
• Discovery year
  1995-11-08
• Entrez gene record
  4726
• Pubmed identfication
  • 9763677
• RefSeq identity
  • NM_004553
• Classification
  • NADH:ubiquinone oxidoreductase supernumerary subunits
• VEGA ID
  OTTHUMG00000090372

Gene info

• Identity
  HGNC:7708
• Gene
  NDUFS2
• Long gene name
  NADH:ubiquinone oxidoreductase core subunit S2
• Synonyms gene name
  • NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Q reductase)
  • NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
• Synonyms
  • CI-49
• Synonyms name
  • complex I 49kDa subunit
  • NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
• GenBank acession
  • BC008868
• Locus
  1q23.3
• Discovery year
  1992-06-30
• Entrez gene record
  4720
• Pubmed identfication
  • 1832859
  • 9585441
• RefSeq identity
  • NM_004550
• Classification
  • NADH:ubiquinone oxidoreductase core subunits
• VEGA ID
  OTTHUMG00000034344

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