CALR Recombinant Protein

• Catalog number
  XW-RP3028
• Price
  Please ask
• Size
  0.1 mg

• About recombinant protein
  Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
• Other name of the recombinant
  RO, CRT, SSA, cC1qR, HEL-S-99n, CRTC, Calreticulin, CRP55, ERp60
• Recombinant in
  E. coli
• SEQUENCE
  aa. 18-417
• Activity
  not available
• Use of recmbinant
  This recombinant protein can be used for WB, ELISA, MS.
• Protein is used in
  E, WB, MS
• Suspention medium
  10 mM Tris, pH 8.0, 0.002% NaN3, 3mM NaCl, 2.5mM
• Keep at
  Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  4757900
• Accession nr
  NP_004334
• KDa of reombinant
  46 kDa (Calculated)
• Pureity
  ~90%
• About
  For research use only.
• Protein s origin
  Human
• NCBI ID
  811
• Gene name
  calreticulin
• Source
  Homo sapiens
• Uniprot
  P27797
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CALR   Protein  
• Gene symbol
  CALR
• Short name
  CALR Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  calreticulin Rec. Protein
• Alternative technique
  rec
• Alternative to gene target
  calreticulin, cC1qR and CRT and HEL-S-99n and RO and SSA, CALR and IDBG-31410 and ENSG00000179218 and 811, chaperone binding, nuclei, Calr and IDBG-174959 and ENSMUSG00000003814 and 12317, CALR and IDBG-642890 and ENSBTAG00000015114 and 281036

Gene info

• Identity
  HGNC:1455
• Gene
  CALR
• Long gene name
  calreticulin
• Synonyms
  • RO
  • SSA
  • cC1qR
  • CRT
  • FLJ26680
• Synonyms name
  • Sicca syndrome antigen A (autoantigen Ro; calreticulin)
  • autoantigen Ro
• GenBank acession
  • M84739
• Locus
  19p13.13
• Discovery year
  1990-09-10
• Entrez gene record
  811
• Pubmed identfication
  • 2365822
• RefSeq identity
  • NM_004343
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000180574
• Locus Specific Databases
  • LRG_828

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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