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Long name
CAF1p55 Primary Polyclonal Antibody
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Also known as
CAF1p55 PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
CAF1p55
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Specificity
This is a highly specific antibody against CAF1p55.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CAF1p55
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Gene ID number
9730
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
Caf 1; CAF-1; CAF-1 P55 subunit; CAF1 p55 subunit; CAF1A; CAF1P55; chaf1b; Chromatin assembly factor 1 p55 subunit; Chromatin assembly factor 1 p60 subunit; chromatin assembly factor 1 subunit; Chromatin assembly factor I; dCAF-1; dCAF1; Human chromatin assembly factor-I p55 subunit; Nucleosome remodeling factor 55 kDa subunit; NURF 55; NURF-55; p55; Probable histone binding protein Caf1; VPRBP_HUMAN.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
