DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3)

• Catalog number
  MBS603001
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [DARC]
• Products_name_syn
  [Anti -DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3)]
• Other_names
  [Duffy antigen/chemokine receptor isoform a; Duffy antigen/chemokine receptor; Duffy antigen/chemokine receptor; glycoprotein D; Fy glycoprotein; Duffy blood group antigen; plasmodium vivax receptor; atypical chemokine receptor 1; Duffy blood group, chemokine receptor; Duffy blood group, atypical chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; Plasmodium vivax receptor]
• Other_gene_names
  [DARC; DARC; FY; Dfy; GPD; GpFy; ACKR1; CCBP1; CD234; WBCQ1; FY; GPD; GpFy]
• Clonality
  Monoclonal
• Clone
  [7H31]
• Reactivity
  Human
• Specificity
  Recognizes human DARC.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol.
• Storage_stability
  Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Flow Cytometry (FC/FACS)
• Description
  cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Adhesion Molecule 3, CADM3). Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.

• Gene target
  DARC   Duffy   Glycoprotein   GpFy   Adhesion   Molecule   CADM3  
• Gene symbol
  CADM3-AS1, ACKR1, CADM3
• Short name
  DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Adhesion Molecule 3, CADM3)
• Technique
  antigen, antigenes
• Host
  Mouse
• Isotype
  IgG2a
• Alternative name
  Duffy blood group, chemokine receptor (Duffy protein, Fy Glycoprotein, GpFy, cellular Adhesion Molecule 3, cellular adhesion molecule 3)
• Alternative technique
  antigenes
• Alternative to gene target
  cell adhesion molecule 3, CADM3 and IDBG-103868 and ENSG00000162706 and 57863, protein homodimerization activity, Cell surfaces, Cadm3 and IDBG-205840 and ENSMUSG00000005338 and 94332, CADM3 and IDBG-630783 and ENSBTAG00000003217 and 531178
• Tissue
  cell

Gene info

• Identity
  HGNC:40812
• Gene
  CADM3-AS1
• Long gene name
  CADM3 antisense RNA 1
• Synonyms
  • CTA-134P22.2
• Locus
  1q23.2
• Discovery year
  2014-02-01
• Entrez gene record
  100131825
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000037178

Gene info

• Identity
  HGNC:4035
• Gene
  ACKR1
• Long gene name
  atypical chemokine receptor 1 (Duffy blood group)
• Synonyms gene
  • FY
  • DARC
• Synonyms gene name
  • Duffy blood group
  • Duffy blood group, chemokine receptor
  • Duffy blood group, atypical chemokine receptor
• Synonyms
  • CCBP1
  • GPD
  • Dfy
  • CD234
• Synonyms name
  • atypical chemokine receptor 1
  • glycoprotein D
• GenBank acession
  • U01839
• Locus
  1q23.2
• Discovery year
  2001-06-22
• Entrez gene record
  2532
• Pubmed identfication
  • 8248172
  • 7663520
  • 16148
• RefSeq identity
  • NM_002036
• Classification
  • Atypical chemokine receptors
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000037182
• Locus Specific Databases
  • LRG_801

Gene info

• Identity
  HGNC:17601
• Gene
  CADM3
• Long gene name
  cell adhesion molecule 3
• Synonyms gene
  • IGSF4B
• Synonyms gene name
  • immunoglobulin superfamily, member 4B
• Synonyms
  • BIgR
  • FLJ10698
  • TSLL1
  • NECL1
  • SynCAM3
  • Necl-1
• Synonyms name
  • nectin-like 1
• GenBank acession
  • AY046418
• Locus
  1q23.2
• Discovery year
  2004-02-24
• Entrez gene record
  57863
• Pubmed identfication
  • 11536053
• RefSeq identity
  • NM_021189
• Classification
  • Nectins and nectin-like molecules
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000037177

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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