CACNB4/L-type Ca++ CPβ4 Antibody, ALEXA FLUOR 594

  • Catalog number
    bs-11983R-A594
  • Price
    Please ask
  • Size
    100ul
  • Long name
    CACNB4/L-type Ca++ CPβ4 Antibody, ALEXA FLUOR 594 Conjugated
  • Also known as
    Anti-CACNB4/L-type Ca++ CPβ4 PAb ALEXA FLUOR 594
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 594
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    CACNB4/L-type Ca++ CPβ4
  • Specificity
    This is a highly specific antibody against CACNB4/L-type Ca++ CPβ4.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CACNB4/L-type Ca++ CPβ4
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta 4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta 4, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), CACNLB4 or CAB4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    590nm/617nm
  • Synonyms
    CAB4; CACB4_HUMAN; Cacnb4; CACNLB4; Calcium channel voltage dependent beta 4 subunit; Calcium channel voltage dependent subunit beta 4; Calcium channel voltage-dependent subunit beta 4; Dihydropyridine sensitive L type calcium channel beta 4 subunit; EA5; EIG9; EJM; EJM4; Voltage-dependent L-type calcium channel subunit beta-4.
  • Properties
    For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    CACNB4
  • Short name
    Anti-CACNB4/L-type Ca++ CPβ4
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    CACNB4/L-type Ca++ CPβ4 Antibody, ALEXA FLUOR 594
  • Alternative technique
    antibodies
  • Alternative to gene target
    calcium channel, voltage-dependent, beta 4 subunit, CAB4 and CACNLB4 and EA5 and EIG9 and EJM and EJM4 and EJM6, CACNB4 and IDBG-72371 and ENSG00000182389 and 785, protein kinase binding, Plasma membranes, Cacnb4 and IDBG-170902 and ENSMUSG00000017412 and 12298, CACNB4 and IDBG-641796 and ENSBTAG00000002297 and 282161
Gene info
  • Identity
  • Gene
  • Long gene name
    calcium voltage-gated channel auxiliary subunit beta 4
  • Synonyms gene name
    • calcium channel, voltage-dependent, beta 4 subunit
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1997-04-21
  • Entrez gene record
    785
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Membrane associated guanylate kinases
    • Calcium voltage-gated channel auxiliary beta subunits
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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