C5a anaphylatoxin Antibody, ALEXA FLUOR 647

• Catalog number
  bs-0324R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  C5a anaphylatoxin Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-C5a anaphylatoxin PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  C5a anaphylatoxin
• Specificity
  This is a highly specific antibody against C5a anaphylatoxin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  700-755/1680
• Subcellular location
  Secreted
• Source
  KLH conjugated synthetic peptide derived from mouse C5a (725-770aa)
• Gene ID Number
  15139
• Swiss Prot
  P06684
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  C5; He; C5a; Complement C5; Hemolytic complement; Hc
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-C5a anaphylatoxin exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  C5a   anaphylatoxin  
• Gene symbol
  C5
• Short name
  Anti-C5a anaphylatoxin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  C5a anaphylatoxin Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1331
• Gene
  C5
• Long gene name
  complement C5
• Synonyms gene name
  • complement component 5
• Synonyms
  • CPAMD4
  • C5a
  • C5b
• Synonyms name
  • prepro-C5
  • C5a anaphylatoxin
• GenBank acession
  • M57729
• Locus
  9q33.2
• Discovery year
  2001-06-22
• Entrez gene record
  727
• RefSeq identity
  • NM_001735
• Classification
  • C3 and PZP like, alpha-2-macroglobulin domain containing
  • Complement system activation components
  • Receptor ligands
• VEGA ID
  OTTHUMG00000020579
• Locus Specific Databases
  • C5base: Mutation registry for C5 deficiency
  • LRG_28

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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