GEF H1 (Ser886) Antibody, Biotin Conjugated
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Catalog numberbs-2201R-Biotin
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PricePlease ask
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Size0.1ml
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Long nameGEF H1 (Ser886) Polyclonal Antibody, Biotin Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationBiotin
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenGEF H1 Ser886
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SpecificityThis is a highly specific antibody against GEF H1 Ser886.
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ModificationPhosphorylation
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Modification siteSer886
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886
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Gene ID number9181
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Tested applicationsWB, IHC-P
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundGEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation EmissionN/A
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SynonymsGEF H1phospho S886; Arhgef2Ser886; Lbcl1; Lfc; mKIAA0651; AA408978; ARHG2; ARHGEF 2; ARHGEF-2; ARHGEF2; GEF; GEF H1; GEF-H1; GEFH1; LFP40; MGC95068; P40; Prolerating cell nucleolar antigen p40; Protein GEF-H1; rho/rac guanine nucleotide exchange factor GEF 2; rho/rac guanine nucleotide exchange factor 2; rho/rac guanine nucleotide exchange factor.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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Additional conjugationBiotinylated
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French translationanticorps
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Gene target
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Gene symbolRAPGEF5, RAPGEF6, ARHGEF2, RAPGEF2, SLC2A4RG
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Short nameAnti-GEF H1 Ser886
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelBiotin
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Alternative nameAnti-GEF H1 Ser886 PAb Biotin
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 5
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Synonyms gene name
- Rap guanine nucleotide exchange factor (GEF) 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-03-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 6
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Synonyms gene
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Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 2
- Rap guanine nucleotide exchange factor (GEF) 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-09-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRho/Rac guanine nucleotide exchange factor 2
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Synonyms gene name
- rho/rac guanine nucleotide exchange factor (GEF) 2
- Rho/Rac guanine nucleotide exchange factor (GEF) 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dbl family Rho GEFs
- Pleckstrin homology domain containing
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 2
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Synonyms gene
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Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 1
- Rap guanine nucleotide exchange factor (GEF) 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-05-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSLC2A4 regulator
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data