HES1 Antibody, ALEXA FLUOR 350

  • Catalog number
    bs-2972R-A350
  • Price
    Please ask
  • Size
    100ul
  • Long name
    HES1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
  • Also known as
    Anti-HES1 PAb ALEXA FLUOR 350
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 350
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    HES1
  • Specificity
    This is a highly specific antibody against HES1.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    40-90/280
  • Subcellular location
    Nucleus
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HES1
  • Gene ID Number
    3280
  • Swiss Prot
    Q14469
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    343nm/442nm
  • Synonyms
    HHL; HRY; HES-1; bHLHb39; Transcription factor HES-1; Class B basic helix-loop-helix protein 39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like protein; HES1; HL
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 350
  • French translation
    anticorps
  • Gene target
    HES1  
  • Gene symbol
    HES1, GATD3
  • Short name
    Anti-HES1
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 350
  • Alternative name
    HES1 Polyclonal Antibody, ALEXA FLUOR 350
  • Alternative technique
    antibodies
  • Alternative to gene target
    hairy and enhancer of split 1, (Drosophila), bHLHb39 and HES-1 and HHL and HRY, HES1 and IDBG-70185 and ENSG00000114315 and 3280, N-box binding, nuclei, Hes1 and IDBG-151888 and ENSMUSG00000022528 and 15205, HES1 and IDBG-634294 and ENSBTAG00000000569 and 539547
Gene info
  • Identity
  • Gene
  • Long gene name
    hes family bHLH transcription factor 1
  • Synonyms gene
  • Synonyms gene name
    • hairy homolog (Drosophila)
    • hairy and enhancer of split 1, (Drosophila)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-09-21
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Basic helix-loop-helix proteins
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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