C1QC/C1QG Antibody, ALEXA FLUOR 647

• Catalog number
  bs-11337R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  C1QC/C1QG Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-C1QC/C1QG PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  C1QC/C1QG
• Specificity
  This is a highly specific antibody against C1QC/C1QG.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C1QC
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA, as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury. Defects in C1q-A, C1q-B and C1q-C cause inactivation of the classical pathway, leading to a rare genetic disorder characterized by lupus-like symptoms.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  C1Q C; C1qc; C1QC_HUMAN; C1QG; Complement C1q subcomponent subunit C; Complement component 1, q subcomponent, C chain; complement component 1, q subcomponent, gamma polypeptide; AI385742.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-C1QC/C1QG exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  C1QC/C1QG  
• Gene symbol
  C1QC
• Short name
  Anti-C1QC/C1QG
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  C1QC/C1QG Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  complement component 1, q subcomponent, C chain, C1Q-C and C1QG, C1QC and IDBG-93737 and ENSG00000159189 and 714, protein binding, Extracellular, C1qc and IDBG-198256 and ENSMUSG00000036896 and 12262, C1QC and IDBG-645502 and ENSBTAG00000011193 and 509968

Gene info

• Identity
  HGNC:1245
• Gene
  C1QC
• Long gene name
  complement C1q C chain
• Synonyms gene
  • C1QG
• Synonyms gene name
  • complement component 1, q subcomponent, gamma polypeptide
  • complement component 1, q subcomponent, C chain
• GenBank acession
  • AK057792
• Locus
  1p36.12
• Discovery year
  1991-09-12
• Entrez gene record
  714
• Pubmed identfication
  • 1706597
• RefSeq identity
  • NM_172369
• Classification
  • Complement system activation components
  • C1q domain containing
• VEGA ID
  OTTHUMG00000002891
• Locus Specific Databases
  • C1QCbase: Mutation registry for C1qC deficiency
  • LRG_24

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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