c-Fos (Thr325) Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-3154R-A555
  • Price
    Please ask
  • Size
    100ul
  • Long name
    c-Fos (Thr325) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-c-Fos Thr325 PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    c-Fos Thr325
  • Specificity
    This is a highly specific antibody against c-Fos Thr325.
  • Modification
    Phosphorylation
  • Modification Site
    Thr325
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    300-350/380
  • Subcellular location
    Cytoplasm, Nucleus
  • Source
    KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Thr325
  • Gene ID Number
    2353
  • Swiss Prot
    P01100
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    p55; AP-1; C-FOS; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7; FOS; G0S7
  • Properties
    For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 555
  • French translation
    anticorps
  • Gene target
    c-Fos   Thr325  
  • Short name
    Anti-c-Fos Thr325
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 555
  • Alternative name
    c-Fos (Thr325) Polyclonal Antibody, ALEXA FLUOR 555
  • Alternative technique
    antibodies
  • Alternative to gene target
    FBJ murine osteosarcoma viral oncogene homolog, AP-1 and C-FOS and p55, FOS and IDBG-12957 and ENSG00000170345 and 2353, R-SMAD binding, nuclei, Fos and IDBG-158538 and ENSMUSG00000021250 and 14281, FOS and IDBG-646869 and ENSBTAG00000004322 and 280795
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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