c-ABL(Tyr204) Antibody, ALEXA FLUOR 488

  • Catalog number
    bs-10353R-A488
  • Price
    Please ask
  • Size
    100ul
  • Long name
    c-ABL(Tyr204) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
  • Also known as
    Anti-c-ABL Tyr204 PAb ALEXA FLUOR 488
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 488
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    c-ABL Tyr204
  • Specificity
    This is a highly specific antibody against c-ABL Tyr204.
  • Modification
    Phosphorylation
  • Modification Site
    Tyr204
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Tyr204
  • Gene ID Number
    25
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    499nm/519nm
  • Synonyms
    c-Ablphospho Y204; c-Ablphospho Tyr204; p-c-AblTyr204; Abelson Murine Leukemia Viral Oncogene Homolog 1; Abelson murine leukemia viral v abl oncogene homolog 1; Abl 1; ABL; Abl protein; Abl1; Bcr/c abl oncogene protein; JTK 7; JTK7; p150; Proto oncogene tyrosine protein kinase ABL1; Transformation gene oncogene ABL; v abl Abelson murine leukemia viral oncogene homolog 1; v abl; ABL1_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-c-ABL Tyr204 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor
  • French translation
    anticorps
  • Gene target
    c-ABL   Tyr204  
  • Gene symbol
    ABL1, MTTP
  • Short name
    Anti-c-ABL Tyr204
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 488
  • Alternative name
    c-ABL(Tyr204) Polyclonal Antibody, ALEXA FLUOR 488
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    ABL proto-oncogene 1, non-receptor tyrosine kinase
  • Synonyms gene
  • Synonyms gene name
    • v-abl Abelson murine leukemia viral oncogene homolog 1
    • c-abl oncogene 1, receptor tyrosine kinase
    • c-abl oncogene 1, non-receptor tyrosine kinase
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1986-01-01
  • Entrez gene record
    25
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Abl family tyrosine kinases
    • SH2 domain containing
  • VEGA ID
  • Locus Specific Databases
Gene info
  • Identity
  • Gene
  • Long gene name
    microsomal triglyceride transfer protein
  • Synonyms gene
  • Synonyms gene name
    • microsomal triglyceride transfer protein (large polypeptide, 88kD)
    • microsomal triglyceride transfer protein (large polypeptide, 88kDa)
  • Synonyms
  • Locus
  • Discovery year
    1994-12-07
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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