C-646,HAT inhibitor

Research Area s

Cell Signaling , Epigenetics
Category

Small Molecules
Product Type

Inhibitor
CAS No

328968-36-1
MolecularFormula

C24H19N3O6
Molecular Weight

445.4
Purity

>98% (TLC), NMR conforms
Solubility

Soluble in 10 mg/ml DMSO
Appearance

Orange Solid
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:24059
Gene

TMPRSS11D
Long gene name

transmembrane serine protease 11D
Synonyms gene name
- transmembrane protease, serine 11D
Synonyms
- HAT
- ASP
Synonyms name
- airway trypsin like protease
- adrenal secretory serine protease
GenBank acession
- AB002134
Locus

4q13.2
Discovery year

2005-03-11
Entrez gene record

9407
Pubmed identfication
- 9565616
- 9070615
RefSeq identity
- NM_004262
Classification
- Type II transmembrane serine proteases
VEGA ID

OTTHUMG00000129300

Identity

HGNC:14013
Gene

SMC4
Long gene name

structural maintenance of chromosomes 4
Synonyms gene
- SMC4L1
Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
Synonyms
- hCAP-C
- CAP-C
GenBank acession
- AF092564
Locus

3q25.33
Discovery year

2001-02-22
Entrez gene record

10051
Pubmed identfication
- 9789013
- 10319587
Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000159006

Identity

HGNC:6776
Gene

MAF
Long gene name

MAF bZIP transcription factor
Synonyms gene name
- v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
Synonyms
- c-MAF
Locus

16q23.2
Discovery year

1991-08-01
Entrez gene record

4094
Pubmed identfication
- 14998484
Classification
- Basic leucine zipper proteins
VEGA ID

OTTHUMG00000137621

Identity

HGNC:9982
Gene

RFX1
Long gene name

regulatory factor X1
Synonyms gene name
- regulatory factor X, 1 (influences HLA class II expression)
Synonyms
- EF-C
Synonyms name
Locus

19p13.12
Discovery year

1991-11-06
Entrez gene record

5989
Pubmed identfication
- 1505960
- 8289803
RefSeq identity
- NM_002918
Classification
- Regulatory factor X family
VEGA ID

OTTHUMG00000181979