C-12 NBD-dihydro-Ceramide

• Catalog number
  N381268
• Price
  Please ask
• Size
  1 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  474943-05-0
• Chemical s molecular weight
  661.92
• Chemical s main applications
  C-12 NBD-dihydro-Ceramide is a fluorescent ceramidase substrate. C-12 NBD-dihydro-Ceramide compound is a fluorescent ceramide analog which contains a saturated bond in the C4-C5 position of the sphingosine backbone. It can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources. C-12 NBD-dihydro-ceramide may exhibit reduced activity in ceramidase assays compared to C-12 NBD ceramide. This is based on the observation that saturation of the C4-C5 sphingosine bond in C16-ceramide results in approximately a 10-fold reduction in efficiency as a substrate for rat brain ceramidase compared to the unsaturated substrate. Yet, experimental characterization of C-12 NBD-dihydro-ceramide as a ceramidase substrate needs to be performed.
• Other name
  6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester
• Chemical s formula
  C36H63N5O6
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications

• Gene target
  C-12   NBD-dihydro-Ceramide  
• Gene symbol
  DGCR2, ERVK3-5, PIRC55, PIRC54, PIRC53, PIRC57, PIRC56, SNORD116-12, IGHV3OR16-12
• Short name
  C-12 NBD-dihydro-Ceramide
• Alternative name
  C-12 NBD-dihydro-Ceramide

Gene info

• Identity
  HGNC:2845
• Gene
  DGCR2
• Long gene name
  DiGeorge syndrome critical region gene 2
• Synonyms
  • KIAA0163
  • LAN
  • IDD
  • DGS-C
  • SEZ-12
• Synonyms name
  • integral membrane protein DGCR2
• GenBank acession
  • D79985
• Locus
  22q11.21
• Discovery year
  2000-07-28
• Entrez gene record
  9993
• Pubmed identfication
  • 7655455
  • 8630060
• RefSeq identity
  • NM_005137
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000150141

Gene info

• Identity
  HGNC:39110
• Gene
  ERVK3-5
• Long gene name
  endogenous retrovirus group K3 member 5
• Synonyms gene name
  • endogenous retrovirus group K3, member 5
• Synonyms
  • HML6-c12
• GenBank acession
  • FR714895
• Locus
  12q24.12
• Discovery year
  2011-05-05
• Pubmed identfication
  • 18077721
  • 21542922

Gene info

• Identity
  HGNC:37559
• Gene
  PIRC55
• Long gene name
  piwi-interacting RNA cluster 55
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313792
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37558
• Gene
  PIRC54
• Long gene name
  piwi-interacting RNA cluster 54
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313815
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37557
• Gene
  PIRC53
• Long gene name
  piwi-interacting RNA cluster 53
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313861
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37561
• Gene
  PIRC57
• Long gene name
  piwi-interacting RNA cluster 57
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313930
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37560
• Gene
  PIRC56
• Long gene name
  piwi-interacting RNA cluster 56
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313862
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33078
• Gene
  SNORD116-12
• Long gene name
  small nucleolar RNA, C/D box 116-12
• Synonyms
  • HBII-85-12
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033424
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003327
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5636
• Gene
  IGHV3OR16-12
• Long gene name
  immunoglobulin heavy variable 3/OR16-12 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-12
• Synonyms
  • IGHV3/OR16-12
• GenBank acession
  • Z29609
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28304
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176355

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