BNIP3L Antibody

• Catalog number
  bs-5798R
• Price
  Please ask
• Size
  0.1ml

• Long name
  BNIP3L Primary Polyclonal Antibody
• Also known as
  BNIP3L PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  BNIP3L
• Specificity
  This is a highly specific antibody against BNIP3L.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  170-219/219
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BNIP3L
• Gene ID number
  665
• Swiss Prot
  O60238
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  NIX; BNIP3a; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; Adenovirus E1B19K-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; NIP3-like protein X; NIP3L; BNIP3L; BNIP3H
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BNIP3L  
• Gene symbol
  BNIP3L
• Short name
  Anti-BNIP3L
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  BNIP3L Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2/adenovirus E1B 19kDa interacting protein 3-like, BNIP3a and NIX, BNIP3L and IDBG-13074 and ENSG00000104765 and 665, protein heterodimerization activity, nuclei, Bnip3l and IDBG-175760 and ENSMUSG00000022051 and 100043324,102641641,12177, BNIP3L and IDBG-635626 and ENSBTAG00000021307 and 534615

Gene info

• Identity
  HGNC:1085
• Gene
  BNIP3L
• Long gene name
  BCL2 interacting protein 3 like
• Synonyms gene name
  • BCL2/adenovirus E1B 19kDa interacting protein 3 like
• Synonyms
  • Nix
  • BNIP3a
• Synonyms name
  • NIP-3-like protein X
• GenBank acession
  • AB004788
• Locus
  8p21.2
• Discovery year
  1997-07-01
• Entrez gene record
  665
• Pubmed identfication
  • 9523198
  • 9973195
• RefSeq identity
  • NM_004331
• VEGA ID
  OTTHUMG00000099433

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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