BMP8B, human recombinant

  • Catalog number
    7304-100
  • Price
    Please ask
  • Size
    100 ug
  • Synonyms
    BMP8, OP2, Bone morphogenetic protein 8B
  • Alternative_names
    BMP8, OP2, Bone morphogenetic protein 8B
  • Description
    Signaling molecule that can induce ectopic bone growth
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥90%
  • Assay
    SDS-PAGE
  • Endotoxin Level
    < 1.0 EU per 1 microgram of protein
  • Molecular Weight
    18.1 kDa (162 aa, 264-402 aa + His tag), confirmed by MALDI-TOF.
  • Storage Temp
    -80°C
  • Shipping
    Dry Ice
  • Shelf Life
    12 months
  • Concentration
    1 mg/ml
  • Appearance
    Liquid
  • Physical form description
    1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol
  • Background Information
    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. Recombinant human BMP8B protein, fused to His-tag at N-terminus, was expressed in E.coli.
  • Amino acid sequence
    MGSSHHHHHH SSGLVPRGSH MGSAVRPLRR RQPKKSNELP QANRLPGIFD DVHGSHGRQV CRRHELYVSF QDLGWLDWVI APQGYSAYYC EGECSFPLDS CMNATNHAIL QSLVHLMMPD AVPKACCAPT KLSATSVLYY DSSNNVILRK HRNMVVKACG CH
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    BMP8B  
  • Gene symbol
    BMP8B-AS1, BMP8B
  • Short name
    BMP8B, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    bone morphogenetic protein 8b, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    bone morphogenetic protein 8b, BMP8 and OP2, BMP8B and IDBG-96764 and ENSG00000116985 and 353500,656, growth factor activity, Extracellular
Gene info
  • Identity
  • Gene
  • Long gene name
    BMP8B antisense RNA 1
  • Locus
  • Discovery year
    2019-05-17
  • Entrez gene record
  • Classification
    • Antisense RNAs
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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