GDF-7 Recombinant Protein
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Catalog number
40-556
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Price
Please ask
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Size
0.002 mg, 0.01 mg
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About recombinant protein
GDF-7 belongs to the TGF-β superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue. Recombinant human GDF-7 is a 28 kDa disulfide linked homodimer containing two 129 amino acid residues.
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Other name of the recombinant
BMP12GDF-7
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Recombinant in
E. coli
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SEQUENCE
TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR
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Activity
Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. Endotoxin level is less than 0.1 ng per μg of GDF-7 (1EU/μg).
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Keep at
The lyophilized GDF-7 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted GDF-7 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing GDF-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI
61835232
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Accession nr
NP_878248.2
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Pureity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
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About
This product is for research use only.
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Protein s origin
Human
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Vial
Lyophilized
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NCBI ID
151449
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Gene name
growth differentiation factor 7
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Source
Homo sapiens
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Uniprot
Q7Z4P5
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
GDF7
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Short name
GDF-7 Recombinant Protein
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
GDF-7 Rec. Protein
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Alternative technique
rec
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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