BMI1 Antibody

• Catalog number
  F51332-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  BMI1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  FACS, WB, IHC, IF, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the BMI1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This BMI1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P35226
• Purity
  Antigen affinity
• Description
  Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. [UniProt]
• Immunogen
  This BMI1 antibody was produced from rabbits immunized with BMI1 recombinant protein.
• Storage
  Aliquot the BMI1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BMI1  
• Gene symbol
  COMMD3-BMI1, BMI1
• Short name
  Anti-BMI1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to BMI1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:48326
• Gene
  COMMD3-BMI1
• Long gene name
  COMMD3-BMI1 readthrough
• Locus
  10p12.2
• Discovery year
  2013-05-08
• Entrez gene record
  100532731
• VEGA ID
  OTTHUMG00000184031

Gene info

• Identity
  HGNC:1066
• Gene
  BMI1
• Long gene name
  BMI1 proto-oncogene, polycomb ring finger
• Synonyms gene
  • PCGF4
• Synonyms gene name
  • polycomb group ring finger 4
  • B lymphoma Mo-MLV insertion region 1 homolog (mouse)
• Synonyms
  • RNF51
• GenBank acession
  • BC011652
• Locus
  10p12.2
• Discovery year
  1994-01-05
• Entrez gene record
  648
• Pubmed identfication
  • 8268912
• RefSeq identity
  • NM_005180
• Classification
  • Polycomb group ring fingers
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000017807

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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