BLZ945

• Catalog number
  B1651-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  BLZ-945, BLZ945; BLZ 945; 4-((2-(((1R,2R)-2-hydroxycyclohexyl)amino)benzo[d]thiazol-6-yl)oxy)-N-methylpicolinamide; 4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-1,3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide
• Description
  BLZ945 is a brain-penetrant CSF-1R kinase inhibitor. The biochemical IC50 for CSF-1R is 1 nM, which is >3200-fold higher than its affinity for other kinases.
• CAS Number
  953769-46-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₂₂N₄O₃S
• Molecular Weight
  398.48
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A brain-penetrant CSF-1R inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD28142668
• PubChem CID
  46184986
• PubChem CID Link
• SMILES
  CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O
• InChi
  InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1
• InChi Key
  ADZBMFGQQWPHMJ-RHSMWYFYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BLZ945  
• Short name
  BLZ945
• Alternative name
  BLZ945

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