BGT226

  • Catalog number
    B1719-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    BGT226; BGT 226; BGT-226; NVP-BGT226; NVPBGT226; NVP BGT226; (Z)-but-2-enedioic acid;8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one; 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt
  • Description
    BGT226 (NVP-BGT226) is a novel inhibitor of class I PI3K/mTOR with IC50 values of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ, respectively.
  • CAS Number
    1245537-68-1
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₃₂H₂₉F₃N₆O₆
  • Molecular Weight
    650.6
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A novel inhibitor of class I PI3K/mTOR
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD22124895
  • PubChem CID
    57336745
  • SMILES
    CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4=CC(=C(C=C4)N5CCNCC5)C(F)(F)F)C6=CN=C(C=C6)OC.C(=CC(=O)O)C(=O)O
  • InChi
    InChI=1S/C28H25F3N6O2.C4H4O4/c1-35-24-16-33-22-6-3-17(18-4-8-25(39-2)34-15-18)13-20(22)26(24)37(27(35)38)19-5-7-23(21(14-19)28(29,30)31)36-11-9-32-10-12-36;5-3(6)1-2-4(7)8/h3-8,13-16,32H,9-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
  • InChi Key
    YUXMAKUNSXIEKN-BTJKTKAUSA-N
  • MSDS Available
    Yes
  • Gene target
    BGT226  
  • Short name
    BGT226
  • Alternative name
    BGT226
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