Beta Catenin (Ser45) Antibody
-
Catalog number
bs-3085R
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
Beta Catenin (Ser45) Primary Polyclonal Antibody
-
Also known as
Beta Catenin (Ser45) PAb
-
Category
Primary Antibodies
-
Conjugation
Unconjugated
-
Target Antigen
Beta Catenin Ser45
-
Specificity
This is a highly specific antibody against Beta Catenin Ser45.
-
Modification s
Phosphorylation
-
Modification site s
Ser45
-
Clonality
Polyclonal antibody
-
Clone number
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
KLH conjugated synthetic phosphopeptide derived from human Beta-Catenin around the phosphorylation site of Ser45
-
Gene ID number
1499
-
Tested Applications
WB, IHC-P, IF(IHC-P)
-
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigen
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym names
beta Catenin phospho S45; beta Catenin phospho Ser45; p-beta Catenin S45; p-beta Catenin Ser45; p-beta Catenin phospho S45; beta-catenin; beta catenin; CTNNB1; CHBCAT; CTNNB1; CTNNB; PRO2286; Cadherin associated protein; Catenin cadherin associated protein, beta 1, 88kDa; Catenin beta 1; Catenin beta-1; CATNB; CTNB1_HUMAN; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; b-catenin; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289.
-
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Short name
Anti-Beta Catenin Ser45
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Host
Rabbit (Oryctolagus cuniculus)
-
Isotype
Immunoglobulin G (IgG)
-
Alternative name
Beta Catenin (Ser45) Polyclonal Antibody
-
Alternative technique
antibodies
-
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products