Bestrophin 4 Antibody

• Catalog number
  bs-11043R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Bestrophin 4 Primary Polyclonal Antibody
• Also known as
  Bestrophin 4 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Bestrophin 4
• Specificity
  This is a highly specific antibody against Bestrophin 4.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bestrophin 4
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BEST 4; BEST4; BEST-4; Bestrophin 4; Bestrophin4; Bestrophin-4; Vitellorm macular dystrophy 2 like 2; Vitellorm macular dystrophy 2 like protein 2; VMD2L2; BEST4_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Bestrophin  
• Gene symbol
  BEST4
• Short name
  Anti-Bestrophin 4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Bestrophin 4 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17106
• Gene
  BEST4
• Long gene name
  bestrophin 4
• Synonyms gene
  • VMD2L2
• Synonyms gene name
  • vitelliform macular dystrophy 2-like 2
• GenBank acession
  • AF440757
• Locus
  1p34.1
• Discovery year
  2003-12-03
• Entrez gene record
  266675
• Pubmed identfication
  • 12032738
  • 16702355
• RefSeq identity
  • NM_153274
• Classification
  • Bestrophins
• VEGA ID
  OTTHUMG00000008488

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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