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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
633-65-8
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Chemical s molecular weight
371.84
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Chemical s main applications
An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
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Chemical s category
Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
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Other name
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride; Berberine Chloride; 7,8,13,13a-Tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium Chloride; Berberine Hydrochloride; NSC 646666;
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Chemical s formula
C20H18ClNO4
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Physical properties
Pale Yellow to Yellow Solid
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Melting temperature
>160°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO, Methanol
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Stability conditions
No Data Available
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Storage
Refrigerator
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