Bcl-2(B cell lymphoma 2) Antibody

• Catalog number
  bs-50514R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Bcl-2(B cell lymphoma 2) Primary Polyclonal Antibody
• Also known as
  Bcl-2(B cell lymphoma 2) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Bcl-2(B cell lymphoma 2)
• Specificity
  This is a highly specific antibody against Bcl-2(B cell lymphoma 2).
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  Recombinant human protein purified from E.coli(His-Bcl-2 1-211 a.a.)
• Gene ID number
  596
• Swiss Prot
  P10415
• Tested Applications
  WB
• Recommended dilutions
  WB (1:2,000)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Bcl-2; PPP1R50; Apoptosis regulator Bcl-2; BCL2
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  For cells, cell lines and tissues in culture till half confluency.
• French translation
  anticorps

• Gene target
  Bcl-2   lymphoma  
• Gene symbol
  BCL2
• Short name
  Anti-Bcl-2(B cell lymphoma 2)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Bcl-2(B cell lymphoma 2) Polyclonal Antibody
• Alternative technique
  antibodies
• Tissue
  cell

Gene info

• Identity
  HGNC:990
• Gene
  BCL2
• Long gene name
  BCL2 apoptosis regulator
• Synonyms gene name
  • B-cell CLL/lymphoma 2
  • BCL2, apoptosis regulator
• Synonyms
  • Bcl-2
  • PPP1R50
• Synonyms name
  • protein phosphatase 1, regulatory subunit 50
• GenBank acession
  • M14745
• Locus
  18q21.33
• Discovery year
  2001-06-22
• Entrez gene record
  596
• RefSeq identity
  • NM_000633
  • NM_000657
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000132791
• Locus Specific Databases
  • LRG_1113

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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