BAX Activator BAM7

BAX Activator BAM7 is available 4 times from Biovision labs

2451-25 | BAX Activator, BAM7 size: 25 mg | 608 USD

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2451-5 | BAX Activator, BAM7 size: 2X5 mg | 393.75 USD

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2451-25 | BAX Activator, BAM7 for cell activation size: 25 mg | 530.41 USD

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2451-5 | BAX Activator, BAM7 for cell activation size: 5 mg | 177.19 USD

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  • Description
    A potent and selective BAX activator (EC₅₀ = 3.3 μM). BAM7 directly binds at the BH3-binding site; selective for BAX over other antiapoptotic and proapoptotic proteins. BAM7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death. BAM7 selectively induces BAX-mediated apoptosis by triggering the hallmark features of intracellular BAX activation. BAM7 only kills the cell line that contains BAX, eliciting the biochemical and morphologic features of BAX-mediated apoptosis.
  • Peptide sequence
    N/A
  • CAS number
    331244-89-4
  • Molecular weight
    405.47
  • Category
    Biochemicals
  • Other name
    3-Methyl-1-(4-phenyl-2-thiazolyl)-1​H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
  • Molecular formula
    C₂₁H₁₉N₅O₂S
  • Physical appearance
    Brown solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    24 months
  • Storage instructions
    Protect from air and light
  • Alternate Name/Synonyms
    3-Methyl-1-(4-phenyl-2-thiazolyl)-1​H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
  • Appearance
    Brown solid
  • Formulation
    N/A
  • CAS Number
    331244-89-4
  • Molecular Formula
    C₂₁H₁₉N₅O₂S
  • Molecular Weight
    405.47
  • Purity
    ≥98% by HPLC
  • Handling
    Protect from air and light
  • Tagline
    A potent and selective BAX activator
  • Storage Temp.
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    N/A
  • PubChem CID
    5754137
  • Alternative to gene target
    BCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730
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