BAX (557CT5.2.1) Monoclonal Antibody

• Catalog number
  bsm-51169M
• Price
  Please ask
• Size
  0.1ml

• Long name
  BAX (557CT5.2.1) Monoclonal Antibody
• Also known as
  BAX (557CT5.2.1) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  BAX
• Specificity
  This is a highly specific antibody against BAX .
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  557CT5.2.1
• Source
  This BAX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from human BAX .
• Gene ID number
  581
• Swiss Prot
  Q07812
• Tested Applications
  WB
• Recommended dilutions
  WB(1:100)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
• Purification method
  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  BAX   557CT5   Monoclonal  
• Gene symbol
  BAX
• Short name
  Anti-BAX
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)2b
• Alternative name
  BAX (557CT5.2.1) Monoclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730

Gene info

• Identity
  HGNC:959
• Gene
  BAX
• Long gene name
  BCL2 associated X, apoptosis regulator
• Synonyms gene name
  • BCL2-associated X protein
  • BCL2 associated X protein
• Synonyms
  • BCL2L4
• Locus
  19q13.33
• Discovery year
  1994-11-08
• Entrez gene record
  581
• Pubmed identfication
  • 8358790
• RefSeq identity
  • NM_138763
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000160476

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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