BAFF Receptor Recombinant Protein
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Catalog number40-306
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PricePlease ask
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Size0.01 mg, 0.05 mg
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About recombinant proteinBAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFFR protein.
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Other name of the recombinantBAFFR, CD268, CVID4, BAFF-R, BROMIX, prolixin, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor
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Recombinant inE. coli
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SEQUENCEMRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
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ActivityBiological activity was determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0 - 4.0 μg/mL in the presence of 1.0μg/mL of human soluble BAFF.
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Keep atThe lyophilized BAFF Receptor recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted BAFF Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing BAFF Receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI16445027
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Accession nrNP_443177.1
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PureityGreater than 95% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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AboutThis product is for research use only.
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Protein s originHuman
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VialLyophilized
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NCBI ID115650
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Gene nametumor necrosis factor receptor superfamily, member 13C
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SourceHomo sapiens
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UniprotQ96RJ3
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolTNFRSF13C
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Short nameBAFF Receptor Recombinant Protein
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative nameBAFF Receptor Rec. Protein
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 13C
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 13C
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-22
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data