AZD-3759

• Catalog number
  9609-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate
• Description
  AZD-3759 is a potent epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. AZD-3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. This prevents EGFR-mediated signaling, and may lead to both induction of cell death and inhibition of tumor growth in EGFR-overexpressing cells.
• CAS Number
  1626387-80-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₃ClFN₅O₃
• Molecular Weight
  459.9
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent epidermal growth factor receptor (EGFR) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  78209992
• PubChem CID Link
• SMILES
  CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C
• InChi
  InChI=1S/C22H23ClFN5O3/c1-13-11-28(2)7-8-29(13)22(30)32-19-9-14-17(10-18(19)31-3)25-12-26-21(14)27-16-6-4-5-15(23)20(16)24/h4-6,9-10,12-13H,7-8,11H2,1-3H3,(H,25,26,27)/t13-/m1/s1
• InChi Key
  MXDSJQHFFDGFDK-CYBMUJFWSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  AZD-3759  
• Short name
  AZD-3759
• Alternative name
  AZD-3759

Product images

Similar products