ATG4D (222CT15.4.1) Monoclonal Antibody

• Catalog number
  bsm-51061M
• Price
  Please ask
• Size
  0.1ml

• Long name
  ATG4D (222CT15.4.1) Monoclonal Antibody
• Also known as
  ATG4D (222CT15.4.1) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ATG4D
• Specificity
  This is a highly specific antibody against ATG4D.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  222CT15.4.1
• Source
  This ATG4D monoclonal antibody is generated from mouse immunized with ATG4D recombinant protein.
• Gene ID number
  84971
• Swiss Prot
  Q86TL0
• Tested Applications
  WB
• Recommended dilutions
  WB(1:1000)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
• Purification method
  Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  APG4D; AUTL4; APG4-D; Cysteine protease ATG4D; AUT-like 4 cysteine endopeptidase; Autophagin-4; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; ATG4D
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  ATG4D   222CT15   Monoclonal  
• Gene symbol
  ATG4D
• Short name
  Anti-ATG4D
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1 κ
• Alternative name
  ATG4D (222CT15.4.1) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20789
• Gene
  ATG4D
• Long gene name
  autophagy related 4D cysteine peptidase
• Synonyms gene
  • AUTL4
  • APG4D
• Synonyms gene name
  • AUT-like 4, cysteine endopeptidase (S. cerevisiae)
  • APG4 autophagy 4 homolog D (S. cerevisiae)
  • ATG4 autophagy related 4 homolog D (S. cerevisiae)
  • autophagy related 4D, cysteine peptidase
• Synonyms
  • APG4-D
• GenBank acession
  • AJ312332
• Locus
  19p13.2
• Discovery year
  2003-04-11
• Entrez gene record
  84971
• Pubmed identfication
  • 12446702
• RefSeq identity
  • NM_032885
• Classification
  • MicroRNA protein coding host genes
  • Autophagy related
• VEGA ID
  OTTHUMG00000180582

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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