AT, antithrombin III

Available ordering format

Liquid
Immunogen

antithrombin III AAB40025
Raised in

Goat
Clonality

Polyclonal
Clone

Polyclonal
Purification

Affinity purified
How to reconstitute

See included datasheet or contact our support service
Storage condition

2-8 °C.
Verified applications

This antibody is suitable for all immunoassay applications
Connected products

antibodies to other proteins involved in coagulation process
Recommended dilutions for use

The optimal working dilution should be determined by the investigator.
Molecular weight expected аpparent

see datasheet
Verified reactivity

human antithrombin III
Possible reactivity

bovine, dog, primates
No reactivity

no confirmed exceptions from predicted reactivity known in the moment
Supplementary information

Affinity purified using solid phase human antithrombin III. Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0).Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preservative. Antibody purity is > 95% based on SDS-PAGE.
References

to be added when available
Scientific context

Antithrombin (AT) is a small glycoprotein which can be found in normal human serum and inactivates several enzymes of the coagulation system.
Notes

None
Protein number

Refer to NCBI
TAIR number

Refer to NCBI
Hyperlink

Gene target

antithrombin III
Gene symbol

CPLX3, MGAT3, MGST3, P4HA3, CASP5, THAP4, IGHVIII-82, MT-CSB3, IGHVIII-67-4, IGHVIII-76-1
Short name

AT, antithrombin III
Alternative name

AT, antithrombin III

Identity

HGNC:7046
Gene

MGAT3
Long gene name

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Synonyms gene name
- mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
Synonyms
- GNT-III
GenBank acession
- D13789
Locus

22q13.1
Discovery year

1993-08-27
Entrez gene record

4248
Pubmed identfication
- 8370666
RefSeq identity
- NM_002409
Classification
- Mannosyl-glycoprotein N-acetylglucosaminyltransferases
VEGA ID

OTTHUMG00000030185

Identity

HGNC:30135
Gene

P4HA3
Long gene name

prolyl 4-hydroxylase subunit alpha 3
Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
- prolyl 4-hydroxylase, alpha polypeptide III
Synonyms
- C-P4Halpha(III)
Synonyms name
- collagen prolyl 4-hydroxylase alpha(III)
GenBank acession
- AY327887
Locus

11q13.4
Discovery year

2004-05-12
Entrez gene record

283208
Pubmed identfication
- 14500733
RefSeq identity
- NM_182904
VEGA ID

OTTHUMG00000165254

Identity

HGNC:1506
Gene

CASP5
Long gene name

caspase 5
Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
Synonyms
- ICE(rel)III
Locus

11q22.3
Discovery year

1996-09-13
Entrez gene record

838
Pubmed identfication
- 7797592
- 9250871
RefSeq identity
- NM_004347
Classification
- Caspases
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000048073

Identity

HGNC:5709
Gene

IGHVIII-82
Long gene name

immunoglobulin heavy variable (III)-82 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (III)-82
- immunoglobulin heavy variable (III)-82 pseudogene
Synonyms
- IGHV(III)-82
GenBank acession
- AB019437
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28338
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151732

Identity

HGNC:5707
Gene

IGHVIII-67-4
Long gene name

immunoglobulin heavy variable (III)-67-4 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (III)-67-4
- immunoglobulin heavy variable (III)-67-4 pseudogene
Synonyms
- IGHV(III)-67-4
GenBank acession
- AB019437
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28340
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151874

Identity

HGNC:5708
Gene

IGHVIII-76-1
Long gene name

immunoglobulin heavy variable (III)-76-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (III)-76-1
- immunoglobulin heavy variable (III)-76-1 pseudogene
Synonyms
- IGHV(III)-76-1
GenBank acession
- AB019437
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28339
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000151872

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data