ASK1 (Ser1033) Antibody

• Catalog number
  bs-5437R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ASK1 (Ser1033) Primary Polyclonal Antibody
• Also known as
  ASK1 (Ser1033) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ASK1 Ser1033
• Specificity
  This is a highly specific antibody against ASK1 Ser1033.
• Modification s
  Phosphorylation
• Modification site s
  Ser1033
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human ASK1 around the phosphorylation site of Ser1033
• Gene ID number
  4217
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ASK1 phospho S1033; Mitogen-activated protein kinase kinase kinase 5; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; Apoptosis signal-regulating kinase 1; ASK-1; MAP3K5; ASK1; MAPKKK5; MEKK5; M3K5_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ASK1   Ser1033  
• Gene symbol
  MAP3K5
• Short name
  Anti-ASK1 Ser1033
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ASK1 (Ser1033) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6857
• Gene
  MAP3K5
• Long gene name
  mitogen-activated protein kinase kinase kinase 5
• Synonyms gene
  • MEKK5
• Synonyms
  • MAPKKK5
  • ASK1
• Synonyms name
  • apoptosis signal regulating kinase 1
• GenBank acession
  • U67156
• Locus
  6q23.3
• Discovery year
  1997-11-14
• Entrez gene record
  4217
• Pubmed identfication
  • 9465908
• Classification
  • Mitogen-activated protein kinase kinase kinases
• VEGA ID
  OTTHUMG00000015647
• Locus Specific Databases
  • The Globin Gene Server

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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