PPARG, Human Recombinant

• Catalog number
  P1120-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Peroxisome proliferator-activated receptor gamma, PPAR-gamma, PPARG, NR1C3, PPARG1, PPARG2
• Alternative_names
  Peroxisome proliferator-activated receptor gamma, PPAR-gamma, PPARG, NR1C3, PPARG1, PPARG2
• Description
  Recombinant Human PPARγ can be used in the inhibition assays, western blotting, ELISA, and numerous such applications
• Recombinant
  Yes
• Source
  E.coli
• Molecular Weight
  80 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Liquid
• Physical form description
  In 50 mM Tris-HCl and 10 mM L-glutathione (reduced).
• Background Information
  Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferators activated receptors (PPARs). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids.
• Amino acid sequence
  MGETLGDSPI DPESDSFTDT LSANISQEMT MVDTEMPFWP TNFGISSVDLSVMEDHSHSF DIKPFTTVDF SSISTPHYED IPFTRTDPVV ADYKYDLKLQEYQSAIKVEP ASPPYYSEKT QLYNKPHEEP SNSLMAIECR VCGDKASGFH YGVHACEGCK GFFRRTIRLK LIYDRCDLNC RIHKKSRNKC QYCRFQKCLA VGMSHNAIRF GRMPQAEKEK LLAEISSDID QLNPESADLR ALAKHLYDSYIKSFPLTKAK ARAILTGKTT DKSPFVIYDM NSLMMGEDKI KFKHITPLQE QSKEVAIRIF QGCQFRSVEA VQEITEYAKS IPGFVNLDLN DQVTLLKYGVHEIIYTMLAS LMNKDGVLIS EGQGFMTREF LKSLRKPFGD FMEPKFEFAV KFNALELDDS DLAIFIAVII LSGDRPGLLN VKPIEDIQDN LLQALELQLKLNHPESSQLF AKLLQKMTDL RQIVTEHV
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PPARG  
• Gene symbol
  PPARG
• Short name
  PPARG, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  peroxisome proliferator-activated receptor gamma, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  peroxisome proliferator-activated receptor gamma, CIMT1 and GLM1 and NR1C3 and PPARG1 and PPARG2 and PPARgamma, PPARG and IDBG-18954 and ENSG00000132170 and 5468, arachidonic acid binding, nuclei, Pparg and IDBG-179253 and ENSMUSG00000000440 and 19016, PPARG and IDBG-646391 and ENSBTAG00000001333 and 281993

Gene info

• Identity
  HGNC:9236
• Gene
  PPARG
• Long gene name
  peroxisome proliferator activated receptor gamma
• Synonyms gene name
  • peroxisome proliferative activated receptor, gamma
  • peroxisome proliferator-activated receptor gamma
• Synonyms
  • PPARG1
  • PPARG2
  • NR1C3
  • PPARgamma
• GenBank acession
  • X90563
• Locus
  3p25.2
• Discovery year
  1996-03-12
• Entrez gene record
  5468
• Pubmed identfication
  • 7862171
  • 9750197
• RefSeq identity
  • NM_005037
• Classification
  • Peroxisome proliferator activated receptors
• VEGA ID
  OTTHUMG00000129764

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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